Faculty of Science, Department of Chemistry, Ganpat University, Gujarat, India.
School of Science, Harbin Institute of Technology, Shenzhen, China.
Luminescence. 2022 Mar;37(3):370-390. doi: 10.1002/bio.4186. Epub 2022 Jan 28.
Amino acids are the most important part of the human biological system due to their role in living processes. The role of amino acids stretches beyond their traditional role as a building block for proteins, and deficiency of amino acids could lead to decreased immunity, digestive problems, depression, fertility issues, lower mental alertness, slowed growth in children, and many other health issues. The acute detection of amino acids is necessary to determine the human health domain. Here, in this review, we summarize and study the calixarenes as complexes that are of immeasurable value and their utilization for amino acid detection. Key factors such as noncovalent forces, limit of detection, and the supramolecular chemistry of calixarenes with amino acids have been well described. This study presents the most recent efforts made towards the development of potential and highly efficient calixarene-based sensors for the detection of amino acids.
氨基酸是人类生物系统最重要的组成部分，因为它们在生命过程中起着重要的作用。氨基酸的作用不仅仅局限于传统的蛋白质合成中的构建块，氨基酸的缺乏可能导致免疫力下降、消化问题、抑郁、生育问题、精神警觉性下降、儿童生长缓慢以及许多其他健康问题。因此，需要对氨基酸进行急性检测以确定人类健康领域。在这篇综述中，我们总结并研究了杯芳烃作为复合物的应用，这些复合物具有不可估量的价值，可用于氨基酸检测。本文详细描述了非共价键、检测限以及杯芳烃与氨基酸的超分子化学等关键因素。本研究介绍了近年来在开发基于杯芳烃的潜在高效氨基酸传感器方面所做的最新努力。
