College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, 311121, China.
Org Biomol Chem. 2022 Jan 26;20(4):790-795. doi: 10.1039/d1ob02249k.
Herein, a protocol that combines heterogeneous catalysis and solar photocatalysis for the regioselective α-substitution of asymmetric ketones with quinoxalinones has been reported. The result indicates that the reaction is more likely to occur on the α-carbon. This strategy provides a green and efficient way for the α-functionalization of ketones. A singlet oxygen involved mechanism is suggested for the transformation.
本文报道了一种将多相催化和太阳能光催化结合用于不对称酮与喹喔啉酮区域选择性α-取代的方法。结果表明，反应更倾向于在α-碳上发生。该策略为酮的α-官能化提供了一种绿色高效的方法。提出了一种涉及单线态氧的转化机制。
