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保留内耳道及小脑脑桥角听神经瘤手术中的听力

Preservation of hearing in surgical removal of acoustic neuromas of the internal auditory canal and cerebellar pontine angle.

作者信息

Nadol J B, Levine R, Ojemann R G, Martuza R L, Montgomery W W, de Sandoval P K

机构信息

Department of Otology and Laryngology, Harvard Medical School, Boston, MA.

出版信息

Laryngoscope. 1987 Nov;97(11):1287-94. doi: 10.1288/00005537-198711000-00007.

Abstract

The surgical results in 69 patients with unilateral tumors of the cerebellopontine angle or internal auditory canal in whom total tumor removal was accomplished, and in whom an attempt was made to preserve hearing, are presented. The success rate of preservation of hearing and facial nerve function was correlated with the size of the tumor. Useful hearing, as defined by speech reception threshold no poorer than 70 dB and a discrimination score of at least 15%, was preserved in 73% of cases in which the tumor extension to the posterior fossa was no greater than 0.5 cm. In contrast, useful hearing was preserved in 22% of cases in which posterior fossa extension was greater than 2.5 cm. No significant correlation was found between preoperative evoked responses and success in preservation of hearing. The techniques and value of intraoperative monitoring of electrocochleogram (ECoG) and brain stem evoked responses are discussed. A theory of pathogenesis of intraoperative hearing loss, based on correlation of changes in evoked responses and simultaneous surgical events, is presented.

摘要

本文介绍了69例桥小脑角或内耳道单侧肿瘤患者的手术结果,这些患者均实现了肿瘤全切,并尝试保留听力。听力和面神经功能的保留成功率与肿瘤大小相关。当肿瘤向后颅窝扩展不超过0.5 cm时,73%的病例保留了有用听力,有用听力定义为言语接受阈不低于70 dB且辨别分数至少为15%。相比之下,当肿瘤向后颅窝扩展大于2.5 cm时,仅22%的病例保留了有用听力。术前诱发反应与听力保留成功之间未发现显著相关性。文中讨论了术中监测耳蜗电图(ECoG)和脑干诱发反应的技术及价值。基于诱发反应变化与同期手术事件的相关性,提出了术中听力损失的发病机制理论。

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