Syntheses and biological properties of 8-carbamoylimidazo[1,2-c]pyrimidines and their heterocyclic analogs.

N-substituted 8-carbamoylimidazo[1,2-c]pyrimidines, 9-carbamoylpyrimido[1,2-c]pyrimidines and 8-carbamoyloxazolo[2,3-c]pyrimidines were obtained by the reaction of N-substituted 5-carbamoyl-2-hydroxy-4-mercapto-6-methylpyrimidines with aminoalcohols or ethylene chlorohydrin. Some of the described compounds exhibit weak antiinflammatory and analgetic effects.