Research on heterocyclic compounds. XXII. Imidazo[1,2-a]pyrimidines.
作者信息
Abignente E, Arena F, Luraschi E, Saturnino C, Berrino L, De Santis D, Marmo E
机构信息
Dipartimento di Chimica Farmaceutica e Tossicologica Facoltà di Farmacia, Università di Napoli, Italy.
出版信息
Farmaco Sci. 1987 Sep;42(9):657-69.
PMID:3500872
Abstract
We have taken into consideration a group of 21 imidazo [1,2-a]pyrimidine derivatives, some of which were already known, whereas the others were synthesized and characterized by us to complete the series. Antiinflammatory, analgesic, antipyretic and ulcerogenic activities of such compounds were evaluated in comparison with indomethacin, in order to get useful information about structure-activity relationships.
摘要
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