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覆膜支架改善了破裂血液透析血管通路的通畅性。

Stent grafts improved patency of ruptured hemodialysis vascular accesses.

机构信息

Division of Cardiology, Department of Medicine, National Taiwan University Hospital Hsinchu Branch, Hsinchu, Taiwan, ROC.

College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.

出版信息

Sci Rep. 2022 Jan 7;12(1):51. doi: 10.1038/s41598-021-03933-1.

Abstract

This study aimed to compare stent graft with balloon tamponade for ruptured dialysis access during percutaneous transluminal angioplasty. Patients over an 8-year period (2010-2018) were identified from a database of 11,609 procedures. The primary endpoint was target lesion primary patency at 12 months. A total of 143 patients who had rupture dialysis access were enrolled, of whom 52 were salvaged by stent grafts and 91 were salvaged by balloon tamponade. The 6-month target lesion primary patency was greater in the stent graft group than in the balloon tamponade group (66.7% vs. 29.5%, P < 0.001). The benefit of stent grafts was sustained for 12 months (52.5% vs. 9.0%, P < 0.001). The stent grafts increased the median time from the index procedure to the next intervention in the ruptured area by 171 days (260 vs. 89 days) at 12 months. There was no significant difference in the access circuit patency rates at 6 months (25.5% vs. 19.8%, P = 0.203) and 12 months (12.0% vs. 5.8%, P = 0.052). The patency results of the stent grafts remained after the multivariable adjustment analysis. Compared to balloon tamponade alone, stent grafts provided superior target lesion primary patency at 6 and 12 months. The access circuit patency rates were similar.

摘要

本研究旨在比较经皮腔内血管成形术治疗透析通路破裂时支架移植物与球囊填塞的效果。从 11609 例手术的数据库中确定了 8 年期间(2010-2018 年)的患者。主要终点是 12 个月时的靶病变一期通畅率。共纳入 143 例破裂透析通路患者,其中 52 例采用支架移植物挽救,91 例采用球囊填塞挽救。支架移植物组的 6 个月靶病变一期通畅率高于球囊填塞组(66.7%比 29.5%,P<0.001)。支架移植物的获益持续到 12 个月(52.5%比 9.0%,P<0.001)。支架移植物组将从指数手术到破裂区域下一次介入的中位数时间从 12 个月时的 171 天(260 天比 89 天)增加。6 个月(25.5%比 19.8%,P=0.203)和 12 个月(12.0%比 5.8%,P=0.052)时的通路循环通畅率无显著差异。支架移植物的通畅率结果在多变量调整分析后仍然存在。与单独使用球囊填塞相比,支架移植物在 6 个月和 12 个月时提供了更好的靶病变一期通畅率。通路循环通畅率相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b23d/8741950/10b915b33a9f/41598_2021_3933_Fig1_HTML.jpg

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