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违背奥卡姆剃刀原理:一例被心脏压塞掩盖的肺栓塞。

Defying Occam's Razor: A Case of Pulmonary Embolism Masked By Cardiac Tamponade.

机构信息

Department of Emergency Medicine, Nepean Hospital, Kingswood, New South Wales, Australia.

Department of Emergency Medicine, Nepean Hospital, Kingswood, New South Wales, Australia; Emergency Ultrasound Training, Nepean Hospital, Kingswood, New South Wales, Australia; Emergency Ultrasound Training, Sydney Adventist Hospital, Wahroonga, New South Wales; The Nepean Clinical School, The University of Sydney, Kingswood, New South Wales, Australia; Emergency Ultrasound Training, Sydney Adventist Hospital, Wahroonga, New South Wales.

出版信息

J Emerg Med. 2022 Feb;62(2):e23-e27. doi: 10.1016/j.jemermed.2021.09.020. Epub 2022 Jan 5.

Abstract

BACKGROUND

Occam's razor instructs physicians to assume one single cause for multiple symptoms, whereas Hickam's dictum encourages them to suspect multiple concurrent pathologies. Although the general practice is to follow Occam's razor, occasionally Hickam's dictum reigns supreme. Here we present one such case, where the concurrent presence of two life-threatening pathologies posed clinical challenges in diagnosis and management.

CASE REPORT

Although cardiac tamponade and pulmonary embolism (PE) are known complications of malignancy, their concomitant existence is rare. Here we report a patient who presented with shortness of breath found to have both cardiac tamponade and submassive PE. Although the cardiac tamponade was initially diagnosed in the Emergency Department by bedside ultrasound and treated with pericardiocentesis, only a few hours later, when she deteriorated, the submassive PE was diagnosed, which was treated with heparin infusion and subsequently transitioned to a newer oral anticoagulant. The patient was later diagnosed as having primary breast cancer and metastatic lung adenocarcinoma. Why Should an Emergency Physician Be Aware of This? This raised unique diagnostic challenges, as both cardiac tamponade and PE present with obstructive shock. The increased right heart pressure from the PE could have paradoxically protected the patient from the tamponade effects of the pericardial effusion. Furthermore, the presence of cardiac tamponade may also mask the typical echocardiographic features of PE. The concurrent presence of two pathologies raised challenges and dilemmas in management. This case shows that physicians should maintain a high degree of suspicion of two pathologies when the patient deteriorates after the first pathology has been appropriately treated.

摘要

背景

奥卡姆剃刀原则指导医生假设多种症状只有一个单一原因,而希卡姆定律则鼓励他们怀疑多种同时存在的病变。尽管通常遵循奥卡姆剃刀原则,但有时希卡姆定律也占主导地位。在这里,我们介绍一个这样的病例,两种危及生命的病变同时存在,在诊断和治疗方面带来了临床挑战。

病例报告

虽然心脏压塞和肺栓塞(PE)是恶性肿瘤的已知并发症,但它们同时存在的情况很少见。在这里,我们报告了一位患者,她因呼吸急促就诊,发现同时存在心脏压塞和亚大面积 PE。尽管心脏压塞最初在急诊室通过床边超声诊断,并通过心包穿刺术进行治疗,但仅在几个小时后,当她病情恶化时,诊断出亚大面积 PE,并给予肝素输注治疗,随后过渡到新型口服抗凝剂。该患者后来被诊断为原发性乳腺癌和转移性肺腺癌。

为什么急诊医生应该了解这一点?这提出了独特的诊断挑战,因为心脏压塞和 PE 都表现为阻塞性休克。PE 引起的右心压力增加可能会使患者免受心包积液的压塞效应。此外,心脏压塞的存在也可能掩盖 PE 的典型超声心动图特征。两种病变的同时存在在管理方面带来了挑战和困境。这个病例表明,当患者在第一个病变得到适当治疗后恶化时,医生应保持对两种病变的高度怀疑。

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