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参与加拿大管理酒精计划与急诊就诊、住院和死亡的关联概率:一项回顾性队列研究。

Participation in Canadian Managed Alcohol Programs and Associated Probabilities of Emergency Room Presentation, Hospitalization and Death: A Retrospective Cohort Study.

机构信息

University of Victoria, Canadian Institute for Substance Use Research (CISUR), 2300 McKenzie Ave, Victoria, BC V8N 5M8, Canada.

Centre for Addiction & Mental Health, Institute for Mental Health Policy Research, 33 Ursula Franklin Street, Toronto, ON M5S 2S1, Canada.

出版信息

Alcohol Alcohol. 2022 Mar 12;57(2):246-260. doi: 10.1093/alcalc/agab078.

DOI:10.1093/alcalc/agab078
PMID:34999760
Abstract

INTRODUCTION

Managed Alcohol Programs (MAPs) are designed to improve health and housing outcomes for unstably housed people with an alcohol use disorder (AUD). The present study assesses the association of MAP participation with healthcare and mortality outcomes.

METHODS

A retrospective cohort study assessed health outcomes for 205 MAP participants and 128 controls recruited from five Canadian cities in 2006-2017. Survival and negative binomial regression models were used to calculate hazard ratios (HR) of death and emergency room (ER) visits and hospital bed days (HBDs). Covariates included age, sex, AUD severity and housing stability score.

RESULTS

In fully adjusted models, compared with times outside MAPs, participants had significantly reduced risk of mortality (HR = 0.37, P = 0.0001) and ER attendance (HR = 0.74, P = 0.0002), and fewer HBDs yearly (10.40 vs 20.08, P = 0.0184). Over the 12 years, people enrolled in a MAP at some point had significantly fewer HBDs per year than controls after MAP enrolment (12.78 vs 20.08, P = 0.0001) but not significantly different rates of death or ER presentation. MAP participants had significantly more alcohol-related but significantly fewer nonalcohol-related ER presentations than controls.

CONCLUSION

Attendance at a MAP was associated with reduced risk of mortality or morbidity and less hospital utilization for individuals with unstable housing and severe AUDs. MAPs are a promising approach to reduce mortality risk and time spent in hospital for people with an AUD and experiencing homelessness.

摘要

简介

管理饮酒项目 (MAP) 旨在改善无家可归且患有酒精使用障碍 (AUD) 的人在健康和住房方面的结果。本研究评估了 MAP 参与与医疗保健和死亡率结果之间的关联。

方法

回顾性队列研究评估了 205 名 MAP 参与者和 128 名对照者的健康结果,这些参与者和对照者于 2006 年至 2017 年期间从加拿大五个城市招募。使用生存和负二项回归模型计算死亡率和急诊室 (ER) 就诊以及住院天数 (HBD) 的风险比 (HR)。协变量包括年龄、性别、AUD 严重程度和住房稳定评分。

结果

在完全调整的模型中,与 MAP 之外的时间相比,参与者的死亡率 (HR=0.37,P=0.0001) 和 ER 就诊率 (HR=0.74,P=0.0002) 风险显著降低,每年的 HBD 也显著减少(10.40 与 20.08,P=0.0184)。在 12 年期间,在某个时候参加 MAP 的人在 MAP 登记后每年的 HBD 明显少于对照组(12.78 与 20.08,P=0.0001),但死亡率或 ER 就诊率没有显著差异。MAP 参与者的酒精相关急诊就诊率明显更高,但非酒精相关急诊就诊率明显更低。

结论

对于不稳定住房和严重 AUD 的个体,参加 MAP 与降低死亡率或发病率风险以及减少医院利用度相关。MAP 是减少 AUD 和无家可归人群死亡率风险和住院时间的一种有前途的方法。

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