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Severe and fatal toxic effects observed in treatment with high- and low-dose leucovorin plus 5-fluorouracil for colorectal carcinoma.

作者信息

Grem J L, Shoemaker D D, Petrelli N J, Douglass H O

出版信息

Cancer Treat Rep. 1987 Nov;71(11):1122.

PMID:3499982
Abstract
摘要

相似文献

1
Severe and fatal toxic effects observed in treatment with high- and low-dose leucovorin plus 5-fluorouracil for colorectal carcinoma.在高剂量和低剂量亚叶酸钙联合5-氟尿嘧啶治疗结直肠癌时观察到严重和致命的毒性作用。
Cancer Treat Rep. 1987 Nov;71(11):1122.
2
[Systemic palliative chemotherapy with 5-fluorouracil and leucovorin in disseminated colorectal cancer].[5-氟尿嘧啶和亚叶酸钙用于播散性结直肠癌的全身姑息化疗]
Ugeskr Laeger. 1999 Jun 21;161(25):3827-32.
3
[An institution-randomized trial of 5-fluorouracil and l-leucovorin therapy given monthly versus every two months to patients with advanced colorectal carcinoma].[一项针对晚期结直肠癌患者的机构随机试验：比较每月与每两个月给予5-氟尿嘧啶和左亚叶酸治疗的效果]
Gan To Kagaku Ryoho. 2004 May;31(5):729-33.
4
Oxaliplatin plus 5-fluorouracil/leucovorin (FOLFOX-4) as salvage chemotherapy in patients with pretreated colorectal cancer.奥沙利铂联合5-氟尿嘧啶/亚叶酸钙（FOLFOX-4）用于经治结直肠癌患者的挽救性化疗。
Gan To Kagaku Ryoho. 2007 Jul;34(7):1079-84.
5
A phase II study of weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin (HDFL) in the treatment of recurrent or metastatic colorectal cancers.一项关于每周24小时输注高剂量5-氟尿嘧啶和亚叶酸（HDFL）治疗复发或转移性结直肠癌的II期研究。
Anticancer Res. 1997 Sep-Oct;17(5B):3867-71.
6
Phase III study of fluorouracil, leucovorin, and levamisole in high-risk stage II and III colon cancer: final report of Intergroup 0089.氟尿嘧啶、亚叶酸钙和左旋咪唑用于高危II期和III期结肠癌的III期研究：肿瘤协作组0089最终报告
J Clin Oncol. 2005 Dec 1;23(34):8671-8. doi: 10.1200/JCO.2004.00.5686.
7
Overview of current status and future direction of clinical trials with 5-fluorouracil in combination with folinic acid.5-氟尿嘧啶联合亚叶酸钙临床试验的现状与未来方向概述
Cancer Treat Rep. 1987 Dec;71(12):1249-64.
8
Clinical studies of biochemical modulation of 5-fluorouracil by leucovorin in patients with advanced colorectal cancer by the North Central Cancer Treatment Group and Mayo Clinic.由北中部癌症治疗组和梅奥诊所开展的关于亚叶酸对晚期结直肠癌患者5-氟尿嘧啶进行生化调节的临床研究。
NCI Monogr. 1987(5):185-8.
9
[Relationship of serum level of dihydropyrimidine dehydrogenase and serum concentration of 5-fluorouracil to treatment response and adverse events in colorectal cancer patients].[血清二氢嘧啶脱氢酶水平和5-氟尿嘧啶血清浓度与结直肠癌患者治疗反应及不良事件的关系]
Ai Zheng. 2005 Apr;24(4):483-7.
10
[Efficacy of m-FOLFOX6 therapy for colorectal cancer in elderly patients].[改良FOLFOX6方案治疗老年结直肠癌患者的疗效]
Gan To Kagaku Ryoho. 2007 Nov;34(11):1833-6.

引用本文的文献

1
Have enteric infections a role in 5-fluorouracil-associated diarrhea?肠道感染在5-氟尿嘧啶相关性腹泻中起作用吗？
Support Care Cancer. 1995 Sep;3(5):322-3. doi: 10.1007/BF00335311.
2
Adjuvant intraperitoneal 5-fluorouracil and intravenous leucovorin after colorectal cancer surgery: a randomized phase II placebo-controlled study.结直肠癌手术后腹腔内注射氟尿嘧啶辅助治疗及静脉注射亚叶酸钙：一项随机II期安慰剂对照研究
Int J Colorectal Dis. 1994 Apr;9(1):35-9. doi: 10.1007/BF00304298.
3
Effects of 5-fluorouracil, leucovorin, and glucarate in rat colon-tumor explants.
5-氟尿嘧啶、亚叶酸和葡糖醛酸在大鼠结肠肿瘤外植体中的作用。
Cancer Chemother Pharmacol. 1992;30(1):25-30. doi: 10.1007/BF00686481.