Department of Urology, San Paolo Hospital, Savona, Italy.
Department of Urology, Careggi University Hospital, Florence, Italy.
World J Urol. 2022 Apr;40(4):1005-1010. doi: 10.1007/s00345-021-03919-8. Epub 2022 Jan 9.
There is currently no consensus regarding the optimal treatment strategy for patients presenting with synchronous bilateral renal masses. The decision to perform bilateral procedures on the same intervention or in staged procedures is debated. The aim of this manuscript is to analyse the outcomes of simultaneous robot-assisted partial nephrectomy (RAPN) in a series of patients with bilateral renal masses treated at five Italian robotic institutions.
Data from a prospectively maintained multi-institutional database on patients subjected to simultaneous RAPN between November 2011 and July 2019 were reviewed. RAPNs were performed with da Vinci Si or Xi surgical system by expert robotic surgeons. Baseline demographics and clinical features, peri- and post-operative data were collected.
Overall, 27 patients underwent simultaneous bilateral RAPN, and 54 RAPNs were performed without need of conversion; median operative time was 250 minutes, median estimated blood loss was 200 mL. Renal artery clamping was needed for 27 (50%) RAPNs with a median warm ischemia time of 15 minutes and no case of acute kidney injury. Complications were reported in 7 (25.9%) patients, mainly represented by Clavien 2 events (6 blood transfusions). Positive surgical margins were assessed in 2 (3.7%) of the renal cell carcinoma. At the median follow-up of 30 months, recurrence-free survival was 100%.
Our data showed that, in selected patients and expert hands, simultaneous bilateral RAPNs could be a safe and feasible procedure with promising results for the treatment of bilateral synchronous renal masses.
目前对于同时存在双侧肾脏肿块的患者,尚无最佳的治疗策略共识。关于同期行双侧手术或分期手术的决策存在争议。本文旨在分析在 5 家意大利机器人机构治疗的一系列双侧肾脏肿块患者中,同时行机器人辅助部分肾切除术(RAPN)的结果。
对 2011 年 11 月至 2019 年 7 月期间接受同期 RAPN 的患者的前瞻性多机构数据库中的数据进行了回顾性分析。RAPN 由达芬奇 Si 或 Xi 手术系统的专家机器人外科医生完成。收集了基线人口统计学和临床特征、围手术期和术后数据。
共有 27 例患者接受了同期双侧 RAPN,54 例 RAPN 无需转为开放手术;中位手术时间为 250 分钟,中位估计失血量为 200ml。27 例(50%)RAPN 需要肾动脉夹闭,中位热缺血时间为 15 分钟,无急性肾损伤病例。7 例(25.9%)患者发生并发症,主要为 Clavien 2 级事件(6 例输血)。2 例(3.7%)肾细胞癌切缘阳性。在中位 30 个月的随访中,无复发生存率为 100%。
我们的数据表明,在选择的患者和专家手中,同期双侧 RAPN 可能是一种安全且可行的方法,对于治疗双侧同步性肾肿块具有良好的结果。