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帕金森病患者的围手术期管理

Peri-operative management of patients with Parkinson's disease.

作者信息

Yim R L H, Leung K M M, Poon C C M, Irwin M G

机构信息

Department of Anaesthesiology, Queen Mary Hospital, Hong Kong, China.

Department of Anaesthesiology, University of Hong Kong, Hong Kong, China.

出版信息

Anaesthesia. 2022 Jan;77 Suppl 1:123-133. doi: 10.1111/anae.15617.

Abstract

Patients with Parkinson's disease are at higher risk of peri-operative medical and surgical complications. Multidisciplinary management, early recognition of potential complications, specialised care of medications and intra-operative protection of the vulnerable brain are all important aspects of the peri-operative management of patients with Parkinson's disease. Advances in continuous dopaminergic treatment, development of a peri-operative Parkinson's disease pathway and application of telemedicine are starting to play a role in improving peri-operative care. Management of patients with advanced Parkinson's disease is also evolving, with potential for incorporation of integrated care and changes in the anaesthetic management for deep brain stimulation surgery. There are new methods for localisation of target nuclei and increasing insight on the effects of anaesthetic drugs on microelectrode recordings and clinical outcomes. Parkinson's disease is a progressive disease, but management is improving with better peri-operative care for patients.

摘要

帕金森病患者围手术期发生内科及外科并发症的风险更高。多学科管理、对潜在并发症的早期识别、药物的专科护理以及术中对脆弱大脑的保护都是帕金森病患者围手术期管理的重要方面。持续多巴胺能治疗的进展、围手术期帕金森病诊疗路径的发展以及远程医疗的应用正开始在改善围手术期护理方面发挥作用。晚期帕金森病患者的管理也在不断发展,有可能纳入综合护理并改变深部脑刺激手术的麻醉管理。出现了新的靶点核团定位方法,并且对麻醉药物对微电极记录及临床结局的影响有了更多认识。帕金森病是一种进行性疾病,但通过为患者提供更好的围手术期护理,其管理正在改善。

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