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与作战人员相关的出血的病理生理学。

Pathophysiology of Hemorrhage as It Relates to the Warfighter.

机构信息

U.S. Army Institute of Surgical Research, JBSA Fort Sam Houston, San Antonio, Texas.

出版信息

Physiology (Bethesda). 2022 May 1;37(3):141-153. doi: 10.1152/physiol.00028.2021. Epub 2022 Jan 10.

Abstract

Saving lives of wounded military warfighters often depends on the ability to resolve or mitigate the pathophysiology of hemorrhage, specifically diminished oxygen delivery to vital organs that leads to multiorgan failure and death. However, caring for hemorrhaging patients on the battlefield presents unique challenges that extend beyond applying a tourniquet and giving a blood transfusion, especially when battlefield care must be provided for a prolonged period. This review describes these challenges and potential strategies for treating hemorrhage on the battlefield in a prolonged casualty care situation.

摘要

挽救受伤的军事作战人员的生命往往取决于解决或减轻出血病理生理学的能力,特别是减少对重要器官的氧气输送,这会导致多器官衰竭和死亡。然而,在战场上照顾出血的患者会带来独特的挑战,这些挑战不仅限于使用止血带和输血,尤其是当必须在长时间内提供战场护理时。本文回顾了这些挑战,并探讨了在长时间伤员救治情况下治疗战场上出血的潜在策略。

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本文引用的文献

1
Cyclosporine A Protects Retinal Explants against Hypoxia.
Int J Mol Sci. 2021 Sep 22;22(19):10196. doi: 10.3390/ijms221910196.
2
Cyclosporine A-enhanced cardioplegia preserves mitochondrial basal respiration after ischemic arrest.
Perfusion. 2024 Jan;39(1):36-44. doi: 10.1177/02676591211025746. Epub 2021 Jun 30.
3
Extremity trauma exacerbates acute kidney injury following prolonged hemorrhagic hypotension.
J Trauma Acute Care Surg. 2021 Aug 1;91(2S Suppl 2):S113-S123. doi: 10.1097/TA.0000000000003311.
5
Centhaquine Restores Renal Blood Flow and Protects Tissue Damage After Hemorrhagic Shock and Renal Ischemia.
Front Pharmacol. 2021 May 3;12:616253. doi: 10.3389/fphar.2021.616253. eCollection 2021.
6
Trauma-induced coagulopathy.
Nat Rev Dis Primers. 2021 Apr 29;7(1):30. doi: 10.1038/s41572-021-00264-3.
7
Physiology of Human Hemorrhage and Compensation.
Compr Physiol. 2021 Feb 12;11(1):1531-1574. doi: 10.1002/cphy.c200016.
8
Endothelial response to glucose: dysfunction, metabolism, and transport.
Biochem Soc Trans. 2021 Feb 26;49(1):313-325. doi: 10.1042/BST20200611.
9
Freeze-dried plasma for major trauma - Systematic review and meta-analysis.
J Trauma Acute Care Surg. 2021 Mar 1;90(3):589-602. doi: 10.1097/TA.0000000000003012.
10
mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion.
Cell Death Dis. 2020 Dec 11;11(12):1050. doi: 10.1038/s41419-020-03239-6.

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