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泰式传统按摩与坦索罗辛治疗下尿路症状的疗效比较:随机对照试验。

A Comparison of Effectiveness of Thai Traditional Massage and Tamsulosin in Lower Urinary Tract Symptoms: A Randomized Controlled Trial.

机构信息

Integrative medicine department, Chulabhorn International College of Medicine, 37698Thammasat University, Thailand.

Division of Urology, Surgery department, Faculty of Medicine, 37698Thammasat University, Thailand.

出版信息

J Evid Based Integr Med. 2022 Jan-Dec;27:2515690X211068825. doi: 10.1177/2515690X211068825.

Abstract

The prospective clinical, non-inferiority study aimed to investigate the effectiveness of Thai traditional massage on lower urinary tract symptoms (LUTS) compared with Tamsulosin in Thai men. It was conducted on men aged 50 to 75 years old with LUTS (N = 45). Participants were blocked four randomly assigned into 2 groups. The control group (n = 25) was received 0.4 mg Tamsulosin daily and the study group (n = 20) was given Thai traditional massage for 4 weeks. The efficacy evaluation was performed by the International Prostate Symptoms Score (IPSS), a Thai version of the World Health Organization Quality of Life Questionnaire (WHO-QoL Brief), Uroflowmetry, and Post-void residual urine (PVR) at baseline and end of study. The background characteristics of participants were not significantly different between groups. Both interventions relieved LUTS in the total IPSS and the quality of life score associated with urination were decreased, described as symptoms and quality of life due to urination improvement after 4 weeks of intervention. Interestingly, the Thai traditional massage has significant improvement in total IPSS and voiding score (p < .05). Additionally, the time to peak flow rate, peak flow rate (Qmax), average flow rate (Qave) and voided volume of both interventions were improved with no statistical significance. PVR was decreased in both interventions. The WHO-QoL brief score was improved the total score. There was no significant difference in terms of uroflowmetry, PVR, and WHO-QoL brief scores compared between groups. The result suggests that Thai traditional massage has the potential to be an alternative treatment for LUTS.

摘要

这项前瞻性、非劣效性临床研究旨在探究与坦索罗辛相比,泰式传统按摩治疗泰国男性下尿路症状(LUTS)的疗效。研究纳入了年龄在 50 至 75 岁之间、患有 LUTS(N=45)的男性。参与者按 4 区随机分为 2 组。对照组(n=25)每日接受 0.4mg 坦索罗辛治疗,研究组(n=20)接受为期 4 周的泰式传统按摩治疗。采用国际前列腺症状评分(IPSS)、泰国世界卫生组织生活质量问卷(WHO-QoL 简表)、尿流率和残余尿量(PVR)评估疗效,于基线和研究结束时进行。两组参与者的背景特征无显著差异。两种干预措施均能缓解总 IPSS 下尿路症状,与排尿相关的生活质量评分降低,表明干预 4 周后症状和排尿相关生活质量得到改善。有趣的是,泰式传统按摩在总 IPSS 和排尿评分方面有显著改善(p<0.05)。此外,两种干预措施均可提高达峰时间、最大尿流率(Qmax)、平均尿流率(Qave)和排尿量,差异无统计学意义。两种干预措施均可降低 PVR。WHO-QoL 简表总分提高。两组间在尿流率、PVR 和 WHO-QoL 简表评分方面无显著差异。该结果表明,泰式传统按摩可能是治疗 LUTS 的一种替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4665/8753073/058022049898/10.1177_2515690X211068825-fig1.jpg

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