Almalki Salman, Alhossan Abdulaziz, Alrumayyan Bashayer, Alanazi Khansa, Bane Gamea Saja, Alesikri Marwa, Ahmad Ajaz, Alrabiah Ziyad
College of Pharmacy, Riyadh Elm University, Riyadh, Saudi Arabia.
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Saudi Pharm J. 2021 Dec;29(12):1426-1431. doi: 10.1016/j.jsps.2021.10.010. Epub 2021 Nov 8.
The present study investigates the aspirin prescribing pattern and guidelines-adherence evaluation for primary prevention of cardiovascular diseases at a teaching hospital. A total of 816 patients were included in the study, the patients who received aspirin aged 60-69 (29.65%), followed by patients aged 50-59 years old (29.53%) and 70-79 years old (22.91%). Demographic information shown that the majority of the patients were males (58.55%). The BMI revealed that 85.78% of patients were obese. The majority of the patients have diabetes 78.67%, hypertension 74.38%, and dyslipidemia 65.68%. The mean systolic blood pressure was 136 ± 7.4 and diastolic blood pressure was 74.9 ± 5.2. After applying aspirin candidacy calculation, only 6% patients were highly recommended to be on aspirin, 49% patients had reasonable recommendation of aspirin, 27% patients use aspirin based on "may be considered" recommendation, and 23% patients were on aspirin with no indication or recommendation. The study highlights the importance of following the international recommendations in aspirin prescribing, and flags the inappropriate use and prescribing by our healthcare providers. The current study encourages further investigation to be carried out which should include patient and clinician education, to well understand and alleviate the inequalities in aspirin use and adherence. Further studies are also warranted to understand of the prescribing pattern and to provide solutions to avoid aspirin associated complications.
本研究调查了一家教学医院心血管疾病一级预防中阿司匹林的处方模式及指南遵循情况评估。共有816名患者纳入研究，接受阿司匹林治疗的患者中60 - 69岁的占29.65%，其次是50 - 59岁的患者（占29.53%）和70 - 79岁的患者（占22.91%）。人口统计学信息显示，大多数患者为男性（占58.55%）。体重指数显示，85.78%的患者肥胖。大多数患者患有糖尿病（占78.67%）、高血压（占74.38%）和血脂异常（占65.68%）。平均收缩压为136±7.4，舒张压为74.9±5.2。应用阿司匹林适用标准计算后，仅6%的患者被强烈推荐使用阿司匹林，49%的患者有合理的阿司匹林使用推荐，27%的患者基于“可考虑”的推荐使用阿司匹林，23%的患者使用阿司匹林但无指征或推荐。该研究强调了在阿司匹林处方中遵循国际推荐的重要性，并指出了我们的医疗服务提供者存在的不当使用和处方问题。当前研究鼓励进一步开展调查，其中应包括患者和临床医生教育，以充分理解和缓解阿司匹林使用及遵循方面的不平等现象。还需要进一步研究以了解处方模式并提供避免阿司匹林相关并发症的解决方案。
