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中国综合医院住院患者常见精神障碍筛查工具的开发

Development of a Screening Tool for Common Mental Disorders Among General Hospital Inpatients in China.

作者信息

Yuan Shuai, Shen Yizhong, Liu Jingwen, Chen Zilin, Zheng Lijiao, Chen Lihao, Chen Hanwei, Feng Huiqiang, He Hongbo

机构信息

Guangzhou Huiai Hospital, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.

Panyu Central Hospital, Guangzhou, China.

出版信息

Front Psychiatry. 2021 Dec 23;12:770255. doi: 10.3389/fpsyt.2021.770255. eCollection 2021.

DOI:10.3389/fpsyt.2021.770255
PMID:35002799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8732762/
Abstract

Depression and anxiety disorders are common conditions among general hospital inpatients, but are believed to be under-recognized in China. A short, practical questionnaire termed the happiness index scale (HIS) was developed for screening co-morbid mental disorders in non-psychiatric clinical settings. The HIS was completed by 1,005 non-psychiatric inpatients in a general hospital in China. The reliability and validity of the HIS were then assessed. The HIS comprised eight items which loaded onto four dimensions: (a) sleep quality; (b) suicidal tendency; (c) depression; and (d) anxiety. These dimensions explained 84.2% of the total variance. Confirmatory factor analysis showed reasonably good fit of the four-factor model (χ/df = 1.27, < 0.001, goodness-of-fit index = 0.95, comparative fit index = 0.99, root-mean-square error of approximation = 0.008). The correlation coefficients between each item and the corresponding factor were all > 0.5. Cronbach's α of the entire scale was 0.83, indicating good internal consistency. The area under the ROC curve was 0.95 compared with the original 31-item scale. Using the optimal cut-off score of HIS (mild happiness), the sensitivity and specificity were 0.933 and 0.882, respectively. The new HIS scale is a practical screening tool composed of eight items covering the four most common and important dimensions of mental disorder. The HIS exhibited good reliability and specificity. The HIS is potentially suitable for large-scale screening in busy non-psychiatric clinical settings in China. Further verification using larger samples is warranted.

摘要

抑郁症和焦虑症在综合医院住院患者中很常见,但在中国被认为未得到充分认识。一种名为幸福指数量表(HIS)的简短实用问卷被开发出来,用于在非精神科临床环境中筛查共病精神障碍。中国一家综合医院的1005名非精神科住院患者完成了HIS问卷。随后对HIS的信效度进行了评估。HIS由八个项目组成,分为四个维度:(a)睡眠质量;(b)自杀倾向;(c)抑郁;(d)焦虑。这些维度解释了总方差的84.2%。验证性因素分析表明四因素模型拟合良好(χ/df = 1.27,< 0.001,拟合优度指数 = 0.95,比较拟合指数 = 0.99,近似均方根误差 = 0.008)。每个项目与相应因素之间的相关系数均> 0.5。整个量表的Cronbach's α为0.83,表明内部一致性良好。与原始的31项量表相比,ROC曲线下面积为0.95。使用HIS的最佳截断分数(轻度幸福),敏感性和特异性分别为0.933和0.882。新的HIS量表是一种实用的筛查工具,由八个项目组成,涵盖了精神障碍最常见和重要的四个维度。HIS表现出良好的信度和特异性。HIS可能适用于中国繁忙的非精神科临床环境中的大规模筛查。有必要使用更大样本进行进一步验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a4/8732762/b7f5455ccfa2/fpsyt-12-770255-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a4/8732762/b7f5455ccfa2/fpsyt-12-770255-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a4/8732762/b7f5455ccfa2/fpsyt-12-770255-g0001.jpg

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