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用碘-123 碘安非他明显示急性脑梗死灶性充血。

Demonstration of focal hyperemia in acute cerebral infarction with iodine-123 iodoamphetamine.

作者信息

Bushnell D L, Gupta S, Mlcoch A G, Romyn A, Barnes W E, Kaplan E

机构信息

Nuclear Medicine Service, Hines VA Hospital, IL 60141.

出版信息

J Nucl Med. 1987 Dec;28(12):1920-3.

PMID:3500290
Abstract

Focal hyperemia is known to occur in regions of acute cerebral infarction. Presented here are two cases in which SPECT images with 125I-labeled iodoamphetamine demonstrated focal areas of increased tracer concentration associated with cerebral infarction. These results may have important implications regarding the physiology of iodoamphetamine in cerebral infarction and, in particular, whether the distribution of this tracer is related to regional blood flow in this setting. In addition, interpretation of iodoamphetamine images in cerebral infarction should include consideration of this finding.

摘要

已知局灶性充血发生在急性脑梗死区域。本文介绍了两例病例,其中用125I标记的碘安非他明的单光子发射计算机断层扫描(SPECT)图像显示与脑梗死相关的示踪剂浓度增加的局灶性区域。这些结果可能对碘安非他明在脑梗死中的生理学具有重要意义,特别是在这种情况下该示踪剂的分布是否与局部血流有关。此外,在脑梗死中对碘安非他明图像的解读应考虑到这一发现。

相似文献

1
Demonstration of focal hyperemia in acute cerebral infarction with iodine-123 iodoamphetamine.用碘-123 碘安非他明显示急性脑梗死灶性充血。
J Nucl Med. 1987 Dec;28(12):1920-3.
2
[A case of subacute cerebral infarction demonstrating hyperemia and crossed cerebellar diaschisis in I-123 IMP SPECT].[123I-异碘代安非他明单光子发射计算机断层扫描显示亚急性脑梗死伴充血和交叉性小脑失联络1例]
Kaku Igaku. 1990 Jul;27(7):749-56.
3
[Brain SPECT with N-isopropyl-p-123I-iodoamphetamine in cerebral infarction].[脑梗死中使用 N-异丙基-p-123I-碘安非他明的脑单光子发射计算机断层扫描]
Rinsho Hoshasen. 1984 Oct;29(10):1141-2.
4
[Regional cerebral blood flow abnormalities detected with N-isopropyl-I-123-p-iodoamphetamine in patients with cerebral infarction].[用N-异丙基-I-123-p-碘安非他明检测脑梗死患者的局部脑血流异常]
Kaku Igaku. 1985 Oct;22(10):1505-13.
5
[Brain imaging with N-isopropyl-p-[123 I] iodoamphetamine].[使用 N-异丙基-p-[123I] 碘安非他明进行脑成像]
Rinsho Hoshasen. 1986 Jun;31(6):677-83.
6
Caudate nucleus infarction demonstrated by N-isopropyl-p iodoamphetamine SPECT imaging using a rotating gamma camera.使用旋转γ相机的N-异丙基-p碘安非他明单光子发射计算机断层扫描成像显示的尾状核梗死。
Clin Nucl Med. 1986 Oct;11(10):718-20. doi: 10.1097/00003072-198610000-00013.
7
Utility of late N-isopropyl-p-(iodine-123)-iodoamphetamine brain distribution in predicting outcome following cerebral infarction.晚期 N-异丙基-p-(碘-123)-碘安非他明脑分布在预测脑梗死预后中的效用
Stroke. 1991 Dec;22(12):1512-8. doi: 10.1161/01.str.22.12.1512.
8
[Remote effects in cerebral infarction--123I-IMP SPECT study].
Kaku Igaku. 1990 Jun;27(6):629-38.
9
Single photon emission computed tomography with tc-99m glucoheptonate and I-123 iodoamphetamine in cerebral infarction.用锝-99m葡庚糖酸盐和碘-123 碘安非他明进行单光子发射计算机断层扫描在脑梗死中的应用
Clin Nucl Med. 1982 Aug;7(8):385. doi: 10.1097/00003072-198208000-00011.
10
Rapid calculation of regional cerebral blood flow and distribution volume using iodine-123-iodoamphetamine and dynamic SPECT.
J Nucl Med. 1995 Apr;36(4):531-6.

引用本文的文献

1
Iodine-123 labelled radiopharmaceuticals and single-photon emission tomography: a natural liaison.碘-123标记的放射性药物与单光子发射断层扫描:一种天然的结合。
Eur J Nucl Med. 1997 Mar;24(3):331-44. doi: 10.1007/BF01728774.
2
Non-matched images with 123I-IMP and 99mTc-bicisate single-photon emission tomography in the demonstration of focal hyperaemia during the subacute phase of an ischaemic stroke.123I-碘代安非他明与99mTc-双半胱乙酯单光子发射断层扫描的不匹配图像在缺血性中风亚急性期局灶性充血显示中的应用
Eur J Nucl Med. 1994 Mar;21(3):254-7. doi: 10.1007/BF00188674.
3
"Luxury perfusion" with 99mTc-HMPAO and 123I-IMP SPECT imaging during the subacute phase of stroke.
在中风亚急性期使用99mTc-HMPAO和123I-IMP单光子发射计算机断层扫描成像进行“强化灌注”。
Eur J Nucl Med. 1990;16(1):17-22. doi: 10.1007/BF01566007.