Koçak Berna, İpek Yeliz
Department of Chemistry and Chemical Process Technologies, Vocational School of Tunceli, Munzur University, 62000 Tunceli, Turkey.
Rare Earth Elements Research and Application Center, Munzur University, 62000 Tunceli, Turkey.
Electrocatalysis (N Y). 2022;13(2):108-115. doi: 10.1007/s12678-021-00704-4. Epub 2022 Jan 5.
In this study, the surface of the glassy carbon electrode was modified with glutardialdehyde. The modified glassy carbon electrode showed electrocatalytic activity against ivermectin. The glassy carbon electrode modified with glutardialdehyde showed high sensitivity, selectivity, and stability in the determination of ivermectin. The peak current of glutardialdehyde oxidation obtained by differential pulse voltammetry decreased inversely with the ivermectin concentration. Ivermectin inhibited the oxidation reaction of glutardialdehyde and caused a decrease in current. This change made the analysis of ivermectin electrochemically possible. In order to demonstrate the applicability of the developed method in real samples, recovery studies were carried out in tap water and urine. The highest sensitivity (0.45 µA/((µmol·L)(cm))) was achieved with urine sample and the lowest detection limit as 2.66 × 10 mol·L was obtained with BRT solution sample.
在本研究中，用戊二醛修饰玻碳电极的表面。修饰后的玻碳电极对伊维菌素表现出电催化活性。用戊二醛修饰的玻碳电极在测定伊维菌素时显示出高灵敏度、选择性和稳定性。通过差分脉冲伏安法获得的戊二醛氧化峰电流与伊维菌素浓度呈反比下降。伊维菌素抑制了戊二醛的氧化反应并导致电流降低。这种变化使得伊维菌素的电化学分析成为可能。为了证明所开发方法在实际样品中的适用性，在自来水和尿液中进行了回收率研究。尿液样品实现了最高灵敏度（0.45 μA/((μmol·L)(cm))），而BRT溶液样品获得了最低检测限为2.66×10⁻⁸ mol·L。
