Diep Cynthia, Karibe Hiroyuki, Goddard Greg, Phan Yen, Shubov Andrew
University of California-Los Angeles, Los Angeles, CA, USA.
Department of Pediatric Dentistry, Nippon Dental University, Tokyo, Japan.
Med Acupunct. 2021 Oct 1;33(5):353-357. doi: 10.1089/acu.2021.0008. Epub 2021 Oct 18.
Gagging is a problem for many dental patients, as well as patients undergoing medical procedures, such as intubation. Research to date on the gag reflex has been limited by a lack of objective measures for measuring this reflex. A validated quantitative method was used to measure if acupuncture or transcutaneous electrical acupoint stimulation (TEAS) at Pericardium 6 (PC 6) and Stomach 36 (ST 36) suppressed the gag reflex, compared with a sham placebo. The subjects were 60 healthy adults randomly chosen to receive acupuncture, TEAS, or sham-TEAS on PC 6, located on the forearm, and ST 36, located on the lower leg. The gag reflex was measured by inserting a saliva ejector slowly down each participant's throat to determine the maximum tolerance of the gag reflex; the insertion length was used as an index of this reflex. There was a significant difference in pre- and postintervention insertion lengths in all groups (paired -test; all groups; < 0.001). The differences in the insertion length among the groups ( = 0.76) and the interaction effect (group × time) were not significant ( = 0.79; 2-way analysis of variance). This study suggested that PC 6 and ST 36 stimulation was no different than placebo for alleviating the gag reflex.
恶心 gagging 对许多牙科患者以及接受诸如插管等医疗程序的患者来说都是个问题。迄今为止,关于恶心反射的研究因缺乏测量该反射的客观方法而受到限制。与假安慰剂相比,采用一种经过验证的定量方法来测量针刺或经皮穴位电刺激(TEAS)内关穴(PC 6)和足三里穴(ST 36)是否能抑制恶心反射。研究对象为60名健康成年人,他们被随机选择在前臂的内关穴(PC 6)和小腿的足三里穴(ST 36)接受针刺、TEAS或假TEAS。通过将一个唾液排出器缓慢插入每个参与者的喉咙来测量恶心反射,以确定恶心反射的最大耐受程度;插入长度被用作该反射的一个指标。所有组干预前后的插入长度存在显著差异(配对t检验;所有组;P<0.001)。组间插入长度的差异(F = 0.76)和交互效应(组×时间)不显著(F = 0.79;双向方差分析)。这项研究表明,刺激内关穴和足三里穴在减轻恶心反射方面与安慰剂没有差异。