Ghasseminia Siyavash, Hareendranathan Abhilash Rakkunedeth, Jaremko Jacob L
Department of Radiology and Diagnostic Imaging, University of Alberta, 2A2.41 WC Mackenzie Health Sciences Centre, 8440 112 Street NW, Edmonton, AB T6G 2B7 Canada.
Indian J Orthop. 2021 Oct 11;55(6):1456-1465. doi: 10.1007/s43465-021-00511-5. eCollection 2021 Dec.
Developmental dysplasia of hip (DDH) represents a spectrum from acetabular dysplasia to fixed dislocation, giving disability through premature osteoarthritis. Most DDH cases continue to present without any known risk factors such as breech presentation, female sex, and family history. Incidence and population-based outcomes of DDH are difficult to reliably establish due to many DDH definitions and classifications using different types of examinations.
This review takes a historical perspective on the role of imaging in DDH.
Pelvic radiographs (X-Ray) were amongst the first medical images identifying DDH, but these have a limited role in infancy due to absent ossification. In the 1980s, ultrasound led to a large expansion in infant DDH screening. Unfortunately, even for well-trained users, DDH indices on ultrasound generally lack reproducibility, and have led to overdiagnosis of mild DDH. CT and MRI more thoroughly evaluate the 3D hip deformity in DDH, but are costly, less available and involve radiation dose and/or anaesthesia.
Recently 3D ultrasound has been used to characterize the 3D deformity of DDH more fully, with improved inter-observer reliability, particularly amongst novice users. 3D ultrasound is also well suited to automated image analysis, but high-resolution 3D probes are costly and not widely available.
Combining the latest handheld portable ultrasound probes and artificial intelligence analysis could lead to an inexpensive tool permitting practical mass population screening for DDH. Overall, our understanding of DDH is heavily influenced by the imaging tools used to visualize it and changing quickly with modern technology.
发育性髋关节发育不良(DDH)涵盖了从髋臼发育不良到固定性脱位的一系列情况,可因过早发生骨关节炎而导致残疾。大多数DDH病例在没有任何已知风险因素(如臀位产、女性性别和家族史)的情况下出现。由于许多DDH的定义和分类使用不同类型的检查,DDH的发病率和基于人群的结局难以可靠确定。
本综述从历史角度探讨影像学在DDH中的作用。
骨盆X线片是最早用于识别DDH的医学影像之一,但由于婴儿期骨化未出现,其在婴儿期的作用有限。20世纪80年代,超声检查使婴儿DDH筛查大幅增加。不幸的是,即使对于训练有素的使用者,超声检查的DDH指标通常也缺乏可重复性,并导致轻度DDH的过度诊断。CT和MRI能更全面地评估DDH中的三维髋关节畸形,但成本高、可用性低,且涉及辐射剂量和/或麻醉。
最近,三维超声已被用于更全面地表征DDH的三维畸形,观察者间的可靠性有所提高,尤其是在新手使用者中。三维超声也非常适合自动图像分析,但高分辨率三维探头成本高且未广泛应用。
结合最新的手持式便携式超声探头和人工智能分析,可能会产生一种廉价工具,允许对DDH进行实际的大规模人群筛查。总体而言,我们对DDH的理解在很大程度上受到用于可视化它的成像工具的影响,并随着现代技术迅速变化。