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用于白内障术前视力筛查的瞳孔引导全息显示

Pupil steering holographic display for pre-operative vision screening of cataracts.

作者信息

Kavaklı Koray, Aydındoğan Güneş, Ulusoy Erdem, Kesim Cem, Hasanreisoğlu Murat, Şahin Afsun, Urey Hakan

机构信息

Koç University, Department of Electrical Engineering, Istanbul, 34450, Turkey.

Koç University Translational Medicine Research Center (KUTTAM), Istanbul, 34450, Turkey.

出版信息

Biomed Opt Express. 2021 Nov 23;12(12):7752-7764. doi: 10.1364/BOE.439545. eCollection 2021 Dec 1.

Abstract

Cataract is the most common cause of preventable blindness and vision loss where the only treatment is surgical replacement of the natural lens with an intraocular lens. Computer-generated holography (CGH) enables to control phase, size, and shape of the light beam entering through the eye-pupil. We developed a holographic vision simulator to assess visual acuity for patients to experience the postoperative corrected vision before going through surgery. A holographically shaped light beam is directed onto the retina using small non-cataractous regions of the lens with the help of a pupil tracker. A Snellen chart hologram is shown to subjects at desired depth with myopia and hyperopia correction. Tests with 13 patients demonstrated substantial improvements in visual acuity and the simulator results are consistent with the post-operative vision tests. Holographic simulator overperforms the existing vision simulators, which are limited to static pinhole exit pupils and incapable of correcting aberrations.

摘要

白内障是可预防的失明和视力丧失的最常见原因,唯一的治疗方法是用人工晶状体手术替换自然晶状体。计算机生成全息术(CGH)能够控制通过眼瞳进入的光束的相位、大小和形状。我们开发了一种全息视觉模拟器,用于评估患者的视力,以便他们在手术前体验术后矫正视力。在瞳孔追踪器的帮助下,使用晶状体的小的无白内障区域将全息形状的光束投射到视网膜上。向受试者展示处于所需深度的、具有近视和远视矫正功能的斯内伦视力表全息图。对13名患者的测试表明视力有显著改善,并且模拟器的结果与术后视力测试结果一致。全息模拟器优于现有的视觉模拟器,现有的视觉模拟器限于静态针孔出瞳,并且无法校正像差。

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