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基于计算全息显示的白内障患者人工晶状体模拟器

Intraocular lens simulator using computational holographic display for cataract patients.

机构信息

Department of Electrical and Electronics Engineering, Koç University, Istanbul, Turkiye.

School of Medicine, Koç University, Istanbul, Turkiye.

出版信息

PLoS One. 2024 Oct 23;19(10):e0295215. doi: 10.1371/journal.pone.0295215. eCollection 2024.

Abstract

PURPOSE

To develop and validate a holography based vision simulator for the demonstration of expected postoperative vision corresponding to monofocal and multifocal intraocular lenses (IOL) to cataract patients before surgery.

METHODS

An artificial eye model is used to measure the optical performance of different IOL types. The resultant aberrations and degradations are then modeled using phase holograms and shown to subjects on a holographic display. We measure the contrast and resolution loss, halos around the light sources, and point spread function (PSF) corresponding to three different IOLs. We tested the holography based vision simulator on 13 healthy subjects and 6 cataract patients.

RESULTS

Monofocal, bifocal, and trifocal IOLs exhibited a contrast decrease of 5%, 42%, and 45% and a resolution limit of 4.49, 4.00, and 4.00 lp/mm (using 0.05 MTF criteria), respectively. Monofocal IOLs have the best resolution and contrast at the optimal focus distance, and multifocal lenses offer extended depth-of-field but exhibit prominent halos and reduced contrast/resolution.

CONCLUSION

We confirmed that the visual functions of IOLs could be successfully modeled using phase holograms and simulated using a holographic display without using a physical IOL. Patients can experience the effects of different IOL options prior to surgery, which helps with IOL selection, expectation management, and patient satisfaction.

摘要

目的

开发和验证一种基于全息术的视觉模拟器,用于在手术前向白内障患者展示单焦点和多焦点人工晶状体(IOL)预期术后视力。

方法

使用人工眼球模型来测量不同 IOL 类型的光学性能。然后使用相位全息图对产生的像差和退化进行建模,并在全息显示器上向受试者展示。我们测量了三种不同 IOL 的对比度和分辨率损失、光源周围的晕圈以及点扩散函数(PSF)。我们在 13 名健康受试者和 6 名白内障患者身上测试了基于全息术的视觉模拟器。

结果

单焦点、双焦点和三焦点 IOL 的对比度分别降低了 5%、42%和 45%,分辨率极限分别为 4.49、4.00 和 4.00 lp/mm(使用 0.05 MTF 标准)。单焦点 IOL 在最佳焦点距离下具有最佳的分辨率和对比度,多焦点镜片具有扩展的景深,但存在明显的晕圈和降低的对比度/分辨率。

结论

我们证实,IOL 的视觉功能可以使用相位全息图成功建模,并使用全息显示器进行模拟,而无需使用物理 IOL。患者可以在手术前体验不同 IOL 选择的效果,这有助于 IOL 选择、期望管理和患者满意度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b391/11498724/26c554ab4338/pone.0295215.g001.jpg

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