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Use of tumor cell lysate to develop peptide vaccine targeting cancer-testis antigens.

作者信息

Malhotra Jyoti, Mehnert Janice M

机构信息

Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.

NYU Grossman School of Medicine and Perlmutter Cancer Center, New York, NY, USA.

出版信息

Transl Lung Cancer Res. 2021 Nov;10(11):4049-4052. doi: 10.21037/tlcr-21-762.

DOI:10.21037/tlcr-21-762
PMID:35004237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8674589/
Abstract
摘要

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Transl Lung Cancer Res. 2021 Jul;10(7):3079-3092. doi: 10.21037/tlcr-21-1.
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Cancer/testis antigens: from serology to mRNA cancer vaccine.癌症/睾丸抗原:从血清学到 mRNA 癌症疫苗。
Semin Cancer Biol. 2021 Nov;76:218-231. doi: 10.1016/j.semcancer.2021.04.016. Epub 2021 Apr 25.
3
A phase II trial of recombinant MAGE-A3 protein with immunostimulant AS15 in combination with high-dose Interleukin-2 (HDIL2) induction therapy in metastatic melanoma.一项在转移性黑色素瘤患者中使用重组 MAGE-A3 蛋白与免疫佐剂 AS15 联合高剂量白细胞介素-2(HDIL2)诱导治疗的 II 期临床试验。
BMC Cancer. 2018 Dec 19;18(1):1274. doi: 10.1186/s12885-018-5193-9.
4
The potential immune-eliciting cancer testis antigens in colorectal cancer.结直肠癌中的潜在免疫原性肿瘤睾丸抗原。
Immunotherapy. 2018 Sep;10(12):1093-1104. doi: 10.2217/imt-2018-0044.
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Current state of immunotherapy for non-small cell lung cancer.非小细胞肺癌免疫治疗的现状
Transl Lung Cancer Res. 2017 Apr;6(2):196-211. doi: 10.21037/tlcr.2017.03.01.
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Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial.MAGE-A3 癌症免疫治疗作为辅助治疗在切除的 MAGE-A3 阳性非小细胞肺癌(MAGRIT)患者中的疗效:一项随机、双盲、安慰剂对照、3 期临床试验。
Lancet Oncol. 2016 Jun;17(6):822-835. doi: 10.1016/S1470-2045(16)00099-1. Epub 2016 Apr 27.
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Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors.五肽癌症疫苗联合环磷酰胺治疗晚期实体瘤的 I 期临床试验。
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Cancer Immunol Immunother. 2015 Oct;64(10):1251-60. doi: 10.1007/s00262-015-1731-3. Epub 2015 Jun 24.
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MAGE-A3: an immunogenic target used in clinical practice.黑色素瘤抗原A3(MAGE - A3):一种临床实践中使用的免疫原性靶点。
Immunotherapy. 2015;7(6):683-704. doi: 10.2217/imt.15.29. Epub 2015 Jun 23.