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基于集成学习的主动脉夹层辅助诊断模型及应用研究

Aortic Dissection Auxiliary Diagnosis Model and Applied Research Based on Ensemble Learning.

作者信息

Luo Jingmin, Zhang Wei, Tan Shiyang, Liu Lijue, Bai Yongping, Zhang Guogang

机构信息

Xiangya Hospital of Central South University, Changsha, China.

Information Science and Engineering School of Central South University, Changsha, China.

出版信息

Front Cardiovasc Med. 2021 Dec 23;8:777757. doi: 10.3389/fcvm.2021.777757. eCollection 2021.

Abstract

Aortic dissection (AD), a dangerous disease threatening to human beings, has a hidden onset and rapid progression and has few effective methods in its early diagnosis. At present, although CT angiography acts as the gold standard on AD diagnosis, it is so expensive and time-consuming that it can hardly offer practical help to patients. Meanwhile, the artificial intelligence technology may provide a cheap but effective approach to building an auxiliary diagnosis model for improving the early AD diagnosis rate by taking advantage of the data of the general conditions of AD patients, such as the data about the basic inspection information. Therefore, this study proposes to hybrid five types of machine learning operators into an integrated diagnosis model, as an auxiliary diagnostic approach, to cooperate with the AD-clinical analysis. To improve the diagnose accuracy, the participating rate of each operator in the proposed model may adjust adaptively according to the result of the data learning. After a set of experimental evaluations, the proposed model, acting as the preliminary AD-discriminant, has reached an accuracy of over 80%, which provides a promising instance for medical colleagues.

摘要

主动脉夹层(AD)是一种威胁人类生命的危险疾病,起病隐匿且进展迅速,早期诊断方法有限。目前,尽管CT血管造影是AD诊断的金标准,但它价格昂贵且耗时,很难为患者提供实际帮助。同时,人工智能技术可能提供一种廉价而有效的方法,利用AD患者的一般状况数据(如基本检查信息数据)来构建辅助诊断模型,以提高AD早期诊断率。因此,本研究提出将五种机器学习算子混合到一个综合诊断模型中,作为一种辅助诊断方法,与AD临床分析相结合。为提高诊断准确性,所提模型中每个算子的参与率可根据数据学习结果进行自适应调整。经过一系列实验评估,所提模型作为初步的AD判别模型,准确率已超过80%,为医学同行提供了一个有前景的实例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c282/8733407/fa9eb2ef5522/fcvm-08-777757-g0001.jpg

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