Aydemir Gozde Aksoy, Bayat Alper Halil, Aydemir Emre, Cinar Serife Sule, Karadag Ayse Sevgi
Department of Ophthalmology, Adıyaman University Training and Research Hospital, Adıyaman, Turkey.
Department of Ophthalmology, Esenler Hospital, Medipol University, Istanbul, Turkey.
Beyoglu Eye J. 2021 Jun 8;6(2):90-95. doi: 10.14744/bej.2021.47568. eCollection 2021.
This study investigated the retinal layer thickness, choroidal thickness (CT), and retinal nerve fiber layer (RNFL) parameters in 3 refractive groups.
A total of 201 eyes of 201 subjects were enrolled in this prospective and comparative study. The patients were divided into 3 groups according to refractive status: Group 1 consisted of 60 eyes of myopic subjects, Group 2 comprised 72 eyes of emmetropic subjects, and 69 eyes of hyperopic subjects were categorized as Group 3. The retinal layer thickness, CT, and RNFL parameters were measured using optical coherence tomography and compared between groups.
The mean age of the patients was 22.33±10.11 years in Group 1, 21.55±8.3 years in Group 2, and 23.73±11.08 years in Group 3 (p=0.741). Group 1 consisted of 34 women and 26 men, Group 2 contained 44 women and 28 men, and Group 3 was made up of 45 women and 24 men (p=0.124). The mean spherical equivalent value was -6.16±2.01 D in Group 1, 0.13±0.5 D in Group 2, and 5.48±1.32 D in Group 3 (p<0.001). The RNFL and macular thickness values were lower in the myopic patients compared with those of the other groups (p<0.05). The CT measurement was lower in the myopic patients and higher in the hyperopic patients compared with the emmetropic patients (p<0.05).
The myopic patients had a lower CT and RNFL thickness measurement than the emmetropic and hyperopic patients, whereas the hyperopic patients had a higher CT than the other patient types.
本研究调查了3个屈光不正组的视网膜各层厚度、脉络膜厚度（CT）及视网膜神经纤维层（RNFL）参数。
本前瞻性比较研究共纳入201例受试者的201只眼。根据屈光状态将患者分为3组：第1组为60只近视受试者的眼，第2组包括72只正视受试者的眼，第3组为69只远视受试者的眼。使用光学相干断层扫描测量视网膜各层厚度、CT及RNFL参数，并在组间进行比较。
第1组患者的平均年龄为22.33±10.11岁，第2组为21.55±8.3岁，第3组为23.73±11.08岁（p=0.741）。第1组由34名女性和26名男性组成，第2组包含44名女性和28名男性，第3组由45名女性和24名男性组成（p=0.124）。第1组的平均等效球镜值为-6.16±2.01 D，第2组为0.13±0.5 D，第3组为5.48±1.32 D（p<0.001）。与其他组相比，近视患者的RNFL和黄斑厚度值较低（p<0.05）。与正视患者相比，近视患者的CT测量值较低，远视患者的CT测量值较高（p<0.05）。
近视患者的CT和RNFL厚度测量值低于正视和远视患者，而远视患者的CT高于其他类型患者。
