Kaderli Ahmet, Acar Mehmet Akif, Ünlü Nurten, Üney Güner Özkan, Örnek Firdevs
Department of Ophthalmology, Ankara Training and Research Hospital, Aleksandr Dubcek St. 4/7 Cankaya, Ankara, Turkey.
Int Ophthalmol. 2018 Apr;38(2):645-653. doi: 10.1007/s10792-017-0509-3. Epub 2017 Apr 4.
This study evaluates the effect of axial length and hyperopia error on macular choroidal thickness as well as choroidal vessel lumen diameter and area with EDI-OCT in short eyes.
The study includes 64 volunteers who are over 18 years of ages and applied to Eye Clinic of Ankara Training and Research Hospital. Choroidal thickness, choroidal vessel lumen diameter and areas were measured with Spectralis OCT device using EDI technique.
The study group included 44 volunteers with hyperopic refractive error, and control group included 20 emmetropic volunteers. Macular choroid was statistically significantly thicker in all quadrants as the hyperopia error increased (p < 0.001). There was a statistically significant negative correlation between axial lengths and macular choroidal thicknesses in all quadrants (p < 0.001). There was a statistically significant difference in choroidal vessel lumen diameter and area between hyperopia groups for both large and small vessels (p < 0.01). The relationships between mean axial length and mean large choroidal vessel diameter and mean area measurements were negatively correlated and they were statistically significant. On the other hand, there was no such negative correlation with small choroidal vessels that have small diameter and area.
Macular choroid thickens as the hyperopic error increases as well as axial length decreases in short eyes. The diameters and areas of noticeable large choroidal vessels in EDI-OCT also increase. These findings in EDI-OCT measurements may play a role in developing population nomograms, as a correcting parameter and in understanding the pathophysiology of certain diseases in short eyes.
本研究使用增强深度成像光学相干断层扫描（EDI-OCT）评估短眼轴患者的眼轴长度和远视误差对黄斑脉络膜厚度以及脉络膜血管腔直径和面积的影响。
本研究纳入了64名年龄超过18岁且前往安卡拉培训与研究医院眼科门诊就诊的志愿者。使用Spectralis OCT设备通过EDI技术测量脉络膜厚度、脉络膜血管腔直径和面积。
研究组包括44名患有远视屈光不正的志愿者，对照组包括20名正视志愿者。随着远视误差增加，所有象限的黄斑脉络膜在统计学上显著增厚（p < 0.001）。所有象限的眼轴长度与黄斑脉络膜厚度之间存在统计学上显著的负相关（p < 0.001）。远视组的大、小血管的脉络膜血管腔直径和面积在统计学上存在显著差异（p < 0.01）。平均眼轴长度与平均大脉络膜血管直径和平均面积测量值之间的关系呈负相关，且具有统计学意义。另一方面，与直径和面积较小的脉络膜小血管不存在这种负相关。
在短眼轴患者中，随着远视误差增加以及眼轴长度缩短，黄斑脉络膜增厚。EDI-OCT中可见的大脉络膜血管的直径和面积也增加。EDI-OCT测量中的这些发现可能在制定人群列线图、作为校正参数以及理解短眼轴患者某些疾病的病理生理学方面发挥作用。
