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铜纳米粒子/聚己内酯/明胶纤维膜的制备具有良好的抗菌活性和机械性能 绿色静电纺丝。

Fabrication of a Cu Nanoparticles/Poly(ε-caprolactone)/Gelatin Fiber Membrane with Good Antibacterial Activity and Mechanical Property Green Electrospinning.

机构信息

Guangdong Engineering & Technology Research Centre of Graphene-like Materials and Products, Department of Chemistry, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, P. R. China.

Department of Light Chemical Engineering, Guangdong Polytechnic, Foshan 528041, P. R. China.

出版信息

ACS Appl Bio Mater. 2021 Aug 16;4(8):6137-6147. doi: 10.1021/acsabm.1c00485. Epub 2021 Aug 1.

DOI:10.1021/acsabm.1c00485
PMID:35006926
Abstract

To improve the antibacterial effect of a poly(ε-caprolactone)/gelatin (PCL/Gt) composite, Cu nanoparticles (Cu NPs) were synthesized as an antibacterial agent, and a Cu NPs/PCL/Gt fiber membrane was thus fabricated green electrospinning. The results showed that the Cu NPs/PCL/Gt fiber membrane with a uniform and complete structure exhibited high porosity and water absorption, favorable hydrophilicity, good mechanical and thermal properties, and satisfactory antibacterial activity. The easy preparation and good comprehensive property implied the great potential application of the Cu NPs/PCL/Gt fiber membrane in various fields (, wound dressing and antibacterial clothing). In addition, the synthesis in this work would offer a promising approach for the preparation of a metal nanoparticle/polymer fiber material with good antibacterial property.

摘要

为提高聚己内酯/明胶(PCL/Gt)复合材料的抗菌效果,将铜纳米粒子(Cu NPs)作为抗菌剂合成,并通过绿色静电纺丝制备了 Cu NPs/PCL/Gt纤维膜。结果表明,具有均匀完整结构的 Cu NPs/PCL/Gt 纤维膜具有高孔隙率和吸水性、良好的亲水性、良好的力学和热性能以及令人满意的抗菌活性。其易于制备和良好的综合性能表明,Cu NPs/PCL/Gt 纤维膜在各个领域(如伤口敷料和抗菌服装)具有巨大的潜在应用价值。此外,本工作的合成方法为制备具有良好抗菌性能的金属纳米粒子/聚合物纤维材料提供了一种有前途的途径。

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