Bulgakov V G, Morgunov A A, Bilenko M V
Biull Eksp Biol Med. 1987 Dec;104(12):643-6.
In experiments on perfused isolated Wistar rat hearts and frog myocardial strips it has been shown that the injection of egg phospholipid liposomes in the perfusion solution leads to a decrease in the volume velocity of the coronary perfusion and to worsening of the contractile myocardial function. Negative inotropic effect of phospholipids on the perfused heart may be linked not only with the decrease in the coronary perfusion but also with their direct inhibitory action on the contractile ability of myocardiocytes.
在对灌注离体Wistar大鼠心脏和青蛙心肌条的实验中发现，向灌注液中注射蛋黄磷脂脂质体可导致冠状动脉灌注的容积速度降低，并使心肌收缩功能恶化。磷脂对灌注心脏的负性肌力作用可能不仅与冠状动脉灌注减少有关，还与其对心肌细胞收缩能力的直接抑制作用有关。
