CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Research Center for Coastal Environmental Engineering Technology of Shandong Province, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China; Department of Polymer Chemistry, Yantai Engineering & Technology College, Yantai 264006, China; University of Chinese Academy of Sciences, Beijing 100049, China.
CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Research Center for Coastal Environmental Engineering Technology of Shandong Province, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
J Hazard Mater. 2022 Apr 15;428:128165. doi: 10.1016/j.jhazmat.2021.128165. Epub 2022 Jan 3.
A novel rotary cloth/paper hybrid microfluidic analytical device (μCPAD) was proposed via the synergy of the fluorescence sensing cloth-based component and rotary paper-based microfluidic analytical device (μPAD) for simultaneous detection of mercury (Hg) and lead (Pb) ions. Fluorescence sensing cloth-based component was prepared by grafting quantum dots onto cotton cloth and then modifying with ion imprinted polymers (IIP). Because the cloth has good ductility and durability, it can bear strong oscillation during the fabrication of grafting quantum dots and IIP, and brings a lot of convenience to the production process. At the same time, because rotary μCPAD was stacked by three-layer papers with designed hydrophilic channels and hydrophobic barriers, it could realize simultaneous detection of Hg and Pb ions by rotating top layer counterclockwise or clockwise. The fluorescence signals were obtained through quantum dots' electron transfer fluorescence quenching effect with the limits of detection were 0.18 and 0.07 μg/L, respectively. This method successfully realized the transference of specific and sensitive fluorescence sensing materials (quantum dots) onto the microfluidic device to improve the portability and expanded applications. Moreover, the novel microfluidic device may have great potential in point-of-care testing of heavy metal ions in environmental monitoring fields.
提出了一种新型旋转布/纸混合微流控分析装置（μCPAD），它通过荧光传感布基组件和旋转纸基微流控分析装置（μPAD）的协同作用，用于同时检测汞（Hg）和铅（Pb）离子。荧光传感布基组件是通过将量子点接枝到棉布上，然后用离子印迹聚合物（IIP）修饰而成的。由于布具有良好的延展性和耐用性，因此在接枝量子点和 IIP 的制备过程中可以承受强烈的振荡，为生产过程带来了很多便利。同时，由于旋转 μCPAD 是由三层具有设计的亲水通道和疏水屏障的纸张堆叠而成的，因此可以通过逆时针或顺时针旋转顶层来实现 Hg 和 Pb 离子的同时检测。通过量子点的电子转移荧光猝灭效应获得荧光信号，检测限分别为 0.18 和 0.07μg/L。该方法成功地将特异性和灵敏的荧光传感材料（量子点）转移到微流控装置上，提高了便携性和应用范围。此外，新型微流控装置在环境监测领域的重金属离子即时检测中可能具有很大的潜力。
