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非洲的类鼻疽病:是时候提高对该病的检测、诊断和治疗的认识和能力建设了。

Melioidosis in Africa: Time to Raise Awareness and Build Capacity for Its Detection, Diagnosis, and Treatment.

机构信息

Division of Infectious Diseases, Department of Medicine and Center for Experimental Molecular Medicine (CEMM), Amsterdam University Medical Centers, AMC, Amsterdam, The Netherlands.

Department of Biochemistry, Nigerian Institute of Medical Research, Lagos, Nigeria.

出版信息

Am J Trop Med Hyg. 2022 Jan 10;106(2):394-397. doi: 10.4269/ajtmh.21-0673.

Abstract

Melioidosis is a tropical infectious disease caused by the soil-dwelling bacterium Burkholderia pseudomallei with a mortality of up to 50% in low resource settings. Only a few cases have been reported from African countries. However, studies on the global burden of melioidosis showed that Africa holds a significant unrecognized disease burden, with Nigeria being at the top of the list. The first World Health Organization African Melioidosis Workshop was organized in Lagos, Nigeria, with representatives of health authorities, microbiology laboratories, and clinical centers from across the continent. Dedicated hands-on training was given on laboratory diagnostics of B. pseudomallei. This report summarises the meeting objectives, including raising awareness of melioidosis and building capacity for the detection, diagnosis, biosafety, treatment, and prevention across Africa. Further, collaboration with regional and international experts provided a platform for sharing ideas on best practices.

摘要

类鼻疽是一种热带传染病,由土壤中生存的伯克霍尔德菌引起,在资源匮乏的环境下,死亡率高达 50%。仅有少数来自非洲国家的报告病例。然而,对类鼻疽全球负担的研究表明,非洲承担着大量未被认识到的疾病负担,尼日利亚位居榜首。第一届世界卫生组织非洲类鼻疽研讨会在尼日利亚拉各斯举行,来自非洲大陆的卫生当局、微生物学实验室和临床中心的代表参加了会议。研讨会还就伯氏考克斯体的实验室诊断进行了专门的实践培训。本报告总结了会议目标,包括提高对类鼻疽的认识,并在整个非洲范围内提高检测、诊断、生物安全、治疗和预防能力。此外,与区域和国际专家的合作提供了一个平台,以分享最佳实践的想法。

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本文引用的文献

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Population-Based Estimate of Melioidosis, Kenya.肯尼亚基于人群的类鼻疽病发病估算。
Emerg Infect Dis. 2019 May;25(5):984-987. doi: 10.3201/eid2505.180545.
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Global Burden and Challenges of Melioidosis.类鼻疽的全球负担与挑战
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Melioidosis.类鼻疽病。
Nat Rev Dis Primers. 2018 Feb 1;4:17107. doi: 10.1038/nrdp.2017.107.

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