Zou Yixin, Yu Haifei, Zhang Li, Ruan Zheng
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing 100048, China.
State Key Laboratory of Food Science and Technology, Institute of Nutrition and School of Food Science, Nanchang University, Nanchang 330047, China.
Foods. 2021 Dec 23;11(1):27. doi: 10.3390/foods11010027.
As the largest immune organ of the human body, the intestine also plays a vital role in nutrient digestion and absorption. Some vegetables are considered to have improvement effects on the intestine. This experiment explored the effects of freeze-dried asparagus, broccoli and cabbage powder on the intestinal immune homeostasis and microflora of mice. Thirty-two mice were divided into four groups ( = 8), including control group (fed normal diet), asparagus group (fed normal diet with 5% asparagus power), broccoli group (fed normal diet with 5% broccoli power) and cabbage group (fed normal diet with 5% cabbage power). The experiment lasted 21 days. The results showed that the serum immunoglobulin concentration (IgA and IgM) and intestinal cytokine content (like IFN-γ and TNF-α) were increased after vegetable powder supplement. The experiment also detected that vegetable powder supplementation changed intestinal flora and their metabolites (short-chain fatty acid), which showed that the abundance of and were decreased, while the abundance of and as well as propionic acid and butyric acid contents were increased. Together, these vegetable powders, especially cabbage, changed the intestinal immune response and microbial activity of mice.
作为人体最大的免疫器官，肠道在营养物质的消化和吸收中也起着至关重要的作用。一些蔬菜被认为对肠道有改善作用。本实验探讨了冻干芦笋、西兰花和卷心菜粉对小鼠肠道免疫稳态和微生物群的影响。将32只小鼠分为四组（每组n = 8），包括对照组（喂食正常饮食）、芦笋组（喂食含5%芦笋粉的正常饮食）、西兰花组（喂食含5%西兰花粉的正常饮食）和卷心菜组（喂食含5%卷心菜粉的正常饮食）。实验持续21天。结果表明，补充蔬菜粉后血清免疫球蛋白浓度（IgA和IgM）和肠道细胞因子含量（如IFN-γ和TNF-α）增加。实验还检测到补充蔬菜粉改变了肠道菌群及其代谢产物（短链脂肪酸），结果显示拟杆菌属和普雷沃菌属丰度降低，而双歧杆菌属和阿克曼菌属丰度以及丙酸和丁酸含量增加。总之，这些蔬菜粉，尤其是卷心菜，改变了小鼠的肠道免疫反应和微生物活性。
