Department of Gastroenterology, "Virgen de las Nieves" University Hospital, 18014 Granada, Spain.
Instituto de Investigación Biosanitaria de Granada (ibs.Granada), 18014 Granada, Spain.
Int J Environ Res Public Health. 2021 Dec 23;19(1):115. doi: 10.3390/ijerph19010115.
(1) Background: Inflammatory bowel disease (IBD) is a chronic inflammatory condition with a significant impact on patients' general health perception. No studies have considered consequences of IBD on cohabitants. (2) Aims: The aims of this study were to address the influence of IBD on cohabitants' quality of life (QoL) and the factors potentially conditioning this impact. (3) Methods: We conducted a cross-sectional study in which IBD patients and their cohabitants were invited to participate. Validated questionnaires were used to measure QoL in patients and cohabitants. Main clinical and sociodemographic variables were collected. (4) Results: A total of 56 patients and 82 cohabitants with significant QoL impairment were included. A direct association was found between Inflammatory Bowel Disease Questionnaire (IBDQ32) score in patients and the Household Members Quality of Life-Inflammatory Bowel Disease (HHMQoL-IBD). IBDQ32 was related to the number of flares in the last 12 months, number of hospital admissions and Mayo Score. (5) Conclusions: HHMQoL-IBD score was related to patients IBDQ32 score and the presence of extraintestinal disease. We identified CRP, a marker of disease activity, as a factor related to cohabitants' quality of life, pointing to a direct relationship of patients' disease activity and their cohabitants' quality of life.
(1) 背景：炎症性肠病（IBD）是一种慢性炎症性疾病，对患者的整体健康感知有重大影响。目前尚无研究探讨 IBD 对同居者的影响。(2) 目的：本研究旨在探讨 IBD 对同居者生活质量（QoL）的影响，以及可能影响这种影响的因素。(3) 方法：我们进行了一项横断面研究，邀请 IBD 患者及其同居者参与。使用经过验证的问卷来测量患者和同居者的 QoL。收集主要的临床和社会人口学变量。(4) 结果：共纳入 56 例患者和 82 例同居者，他们的 QoL 均受到显著影响。患者的炎症性肠病问卷（IBDQ32）评分与家庭成员生活质量-炎症性肠病（HHMQoL-IBD）评分之间存在直接关联。IBDQ32 与过去 12 个月的疾病发作次数、住院次数和 Mayo 评分有关。(5) 结论：HHMQoL-IBD 评分与患者的 IBDQ32 评分和肠外疾病的存在有关。我们发现 CRP，一种疾病活动的标志物，是与同居者生活质量相关的因素之一，这表明患者的疾病活动与他们同居者的生活质量之间存在直接关系。
