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斑秃患者同居者的生活质量和情绪状态紊乱:西班牙人群的横断面研究。

Quality of Life and Mood Status Disturbances in Cohabitants of Patients with Alopecia Areata: A Cross-Sectional Study in a Spanish Population.

机构信息

Dermatology Unit, Hospital Universitario Virgen de las Nieves, 18002 Granada, Spain.

Instituto de Investigación Biosanitaria ibs.GRANADA, 18002 Granada, Spain.

出版信息

Int J Environ Res Public Health. 2022 Dec 6;19(23):16323. doi: 10.3390/ijerph192316323.

DOI:10.3390/ijerph192316323
PMID:36498394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9737113/
Abstract

A poor quality of life has been described in patients suffering from Alopecia Areata (AA). However, there is little evidence on how AA can impact on those living with patients. The aim of this study is to analyze the impact of AA on a cohabitant’s quality-of-life, mood status disturbances and sexual satisfaction. This is a cross-sectional study of AA patients and their cohabitants. Socio-demographic variables and disease severity, the quality of life, mood status disturbances and sexual dysfunction were collected using validated questionnaires. Eighty-four subjects were included in the study: 42 AA patients and 42 cohabitants. A poor quality of life and worse disease control in the patients were associated with a poorer quality of life of the family, higher scores of anxiety and depression, and the lower sexual satisfaction of cohabitants (p < 0.05). Anxiety and depression in patients were associated with worse family quality of life, higher rates of anxiety and less sexual satisfaction in cohabitants (p < 0.05). To conclude, AA seems to have an impact on the quality of life of cohabitants, leading to increased rates of anxiety, depression, a poorer quality of life, and reduced sexual satisfaction. In light of the results, a global approach for AA patients, including the care of the people who live with them, should be implemented.

摘要

斑秃患者的生活质量较差。然而,目前关于斑秃如何影响患者的同住者的证据很少。本研究旨在分析斑秃对同住者生活质量、情绪状态紊乱和性满意度的影响。这是一项斑秃患者及其同住者的横断面研究。采用经过验证的问卷收集社会人口统计学变量和疾病严重程度、生活质量、情绪状态紊乱和性功能障碍。本研究共纳入 84 名受试者:42 名斑秃患者和 42 名同住者。患者生活质量较差和疾病控制较差与家庭生活质量较差、焦虑和抑郁评分较高以及同住者性满意度较低相关(p<0.05)。患者的焦虑和抑郁与同住者的家庭生活质量较差、焦虑发生率较高和性满意度较低相关(p<0.05)。总之,斑秃似乎会影响同住者的生活质量,导致焦虑、抑郁、生活质量下降和性满意度降低。鉴于这些结果,应该对斑秃患者实施包括照顾同住者在内的整体治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3547/9737113/9224c558f6c7/ijerph-19-16323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3547/9737113/9224c558f6c7/ijerph-19-16323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3547/9737113/9224c558f6c7/ijerph-19-16323-g001.jpg

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Tofacitinib for Treatment of Alopecia Areata: Real-world Evidence and Factors Associated with Therapeutic Response.托法替布治疗斑秃:真实世界证据及与治疗反应相关的因素
Acta Derm Venereol. 2022 Jun 15;102:adv00736. doi: 10.2340/actadv.v102.2036.
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Sleep disturbance in alopecia areata: A cross-sectional study.斑秃患者的睡眠障碍:一项横断面研究。
Health Sci Rep. 2022 Apr 1;5(3):e576. doi: 10.1002/hsr2.576. eCollection 2022 Apr.
4
Alopecia Areata and Dexamethasone Mini-Pulse Therapy, A Prospective Cohort: Real World Evidence and Factors Related to Successful Response.斑秃与地塞米松小剂量脉冲疗法:一项前瞻性队列研究,真实世界证据及与成功应答相关的因素
J Clin Med. 2022 Mar 18;11(6):1694. doi: 10.3390/jcm11061694.
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Quality of Life in Cohabitants of Patients Suffering Inflammatory Bowel Disease: A Cross-Sectional Study.炎性肠病患者同居者的生活质量:一项横断面研究。
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Quality of Life in Cohabitants of Patients with Hidradenitis Suppurativa: A Cross-sectional Study.生活质量在合并化脓性汗腺炎患者:一项横断面研究。
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