Department of Allergology and Pulmonology, Medical University of Gdansk, 80-211 Gdansk, Poland.
Department of Rehabilitation Medicine, Faculty of Health Sciences with Institute of Maritime and Tropical Medicine, Medical University of Gdansk, 80-211 Gdansk, Poland.
Int J Environ Res Public Health. 2021 Dec 30;19(1):406. doi: 10.3390/ijerph19010406.
Patients with Duchenne muscular dystrophy (DMD) may be at higher risk of a severe course of COVID-19. The aim of the study was to evaluate: (1) the incidence and course of COVID-19 infection in DMD patients; (2) the vaccination status of DMD patients; and (3) COVID-19 related anxiety among DMD families. The study was conducted during an online symposium for DMD patients and their families. All participants (DMD families; = 150) were asked to fill in the online survey with questions about COVID-19 infection history, vaccination against SARS-CoV-2 and anxiety during pandemic. 53 DMD patients filled in the survey. Five (9.43%) were COVID-19 positive with mild symptoms of respiratory infection and anosmia; 23 (42.6%) were vaccinated, but in almost 20% of DMD families, none of the family members was vaccinated. Respondents revealed anxiety related both to the vaccination procedure and to COVID-19 infection (complications after infection 93.6%, death 62.4% respondents). Changes in health care system organization also aroused concern among participants (85.3%). The course of the COVID-19 infection in DMD patients was mild. Not enough patients with DMD and their families are vaccinated. Education about the management of COVID-19 infections and the vaccination procedure for DMD patients is needed and expected.
杜氏肌营养不良症（DMD）患者可能有更高的 COVID-19 重症风险。本研究的目的是评估：（1）DMD 患者 COVID-19 感染的发病率和病程；（2）DMD 患者的疫苗接种情况；（3）DMD 家庭的 COVID-19 相关焦虑。该研究是在 DMD 患者及其家属的在线研讨会上进行的。所有参与者（DMD 家庭；=150）都被要求在线填写问卷调查，内容涉及 COVID-19 感染史、针对 SARS-CoV-2 的疫苗接种和大流行期间的焦虑情况。53 名 DMD 患者填写了调查。5 人（9.43%） COVID-19 检测呈阳性，表现为呼吸道感染和嗅觉丧失的轻微症状；23 人（42.6%）已接种疫苗，但在近 20%的 DMD 家庭中，没有任何家庭成员接种疫苗。受访者表示对疫苗接种程序和 COVID-19 感染都感到焦虑（感染后并发症 93.6%，死亡 62.4%的受访者）。医疗保健系统组织的变化也引起了参与者的关注（85.3%）。DMD 患者的 COVID-19 感染病程较轻。接受疫苗接种的 DMD 患者和其家庭人数不足。需要并期望对 COVID-19 感染的管理和 DMD 患者的疫苗接种程序进行教育。
