EIO UMR 241, IFREMER, ILM, IRD, Université de la Polynésie Française, BP 6570, F-98702 Faaa, Tahiti, French Polynesia.
Institut Méditerranéen de Biodiversité et d'Ecologie Marine et Continentale (IMBE), UMR 7263 CNRS, IRD, Aix Marseille Université, Avignon Université, Station Marine d'Endoume, rue de la Batterie des Lions, 13007 Marseille, France.
Molecules. 2021 Dec 24;27(1):105. doi: 10.3390/molecules27010105.
The term cosmetopoeia refers to the use of plants in folks' cosmetics. The aerial parts of L., the leaves of L. and the fruits of A.Gray ex Benth are traditionally used in French Polynesia for hair and skin care. During the hair cycle, dermal papilla cells and their interaction with epithelial cells are essential to promote hair follicle elongation. The aim of our investigations was the identification of metabolites from these three plants and chemical families responsible for their hair growth activity. A bioactivity-based molecular network was produced by mapping the correlation between features obtained from LC-MS/MS data and dermal papilla cell proliferation, using the Pearson correlation coefficient. The analyses pointed out glycosylated flavonols and phenolic acids from and , along with C-flavonoids, iridoids and secoiridoids from , as potential bioactive molecules involved in the proliferation of hair follicle dermal papilla cells. Our results highlight the metabolites of the plant species potentially involved in the induction of hair follicle growth and support the traditional uses of these plants in hair care.
术语“化妆品植物学”是指在民间化妆品中使用植物。在法属波利尼西亚，传统上使用 L. 的地上部分、L. 的叶子和 A.Gray ex Benth 的果实来护理头发和皮肤。在头发周期中，真皮乳头细胞及其与上皮细胞的相互作用对于促进毛囊伸长至关重要。我们研究的目的是从这三种植物和化学家族中鉴定出代谢产物，并确定它们促进头发生长活性的物质。通过使用皮尔逊相关系数，将从 LC-MS/MS 数据中获得的特征与真皮乳头细胞增殖之间的相关性映射到基于生物活性的分子网络上。分析指出，来自 和 的糖基化类黄酮和酚酸，以及来自 的 C-类黄酮、环烯醚萜和裂环烯醚萜，是参与毛囊真皮乳头细胞增殖的潜在生物活性分子。我们的结果强调了潜在参与诱导毛囊生长的植物物种的代谢产物，并支持这些植物在头发护理中的传统用途。
