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泌尿科癌症结局与国家人类发展指数的关系:近年来的趋势。

The relationship between urologic cancer outcomes and national Human Development Index: trend in recent years.

机构信息

Department of Urology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, China.

Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.

出版信息

BMC Urol. 2022 Jan 10;22(1):2. doi: 10.1186/s12894-022-00953-5.

DOI:10.1186/s12894-022-00953-5
PMID:35012527
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8744298/
Abstract

OBJECTIVES

To describe the influence of the socioeconomic development on worldwide age-standardized incidence and mortality rates, as well as mortality-to-incidence ratio (MIR) and 5-year net survival of urologic cancer patients in recent years.

METHODS

The Human Development Index (HDI) values were obtained from the United Nations Development Programme, data on age-standardized incidence/mortality rates of prostate, bladder and kidney cancer were retrieved from the GLOBOCAN database, 5-year net survival was provided by the CONCORD-3 program. We then evaluated the association between incidence/MIR/survival and HDI, with a focus on geographic variability as well as temporal patterns during the last 6 years.

RESULTS

Urologic cancer incidence rates were positively correlated with HDIs, and MIRs were negatively correlated with HDIs. Prostate cancer survival also correlated positively with HDIs, solidly confirming the interrelation among cancer indicators and socioeconomic factors. Most countries experienced incidence decline over the most recent 6 years, and a substantial reduction in MIR was observed. Survival rates of prostate cancer have simultaneously improved.

CONCLUSION

Development has a prominent influence on urologic cancer outcomes. HDI values are significantly correlated with cancer incidence, MIR and survival rates. HDI values have risen along with increased incidence and improved outcomes of urologic caner in recent years.

摘要

目的

描述近年来社会经济发展对全球年龄标准化发病率和死亡率以及肿瘤患者死亡率与发病率比(MIR)和 5 年净生存率的影响。

方法

从联合国开发计划署获取人类发展指数(HDI)值,从 GLOBOCAN 数据库获取前列腺癌、膀胱癌和肾癌的年龄标准化发病率/死亡率数据,CONCORD-3 项目提供 5 年净生存率。然后,我们评估了发病率/MIR/生存率与 HDI 之间的关联,重点关注地理变异性以及过去 6 年的时间模式。

结果

泌尿生殖系统癌症的发病率与 HDI 呈正相关,MIR 与 HDI 呈负相关。前列腺癌的生存率也与 HDI 呈正相关,这有力地证实了癌症指标与社会经济因素之间的相互关系。大多数国家在最近 6 年中经历了发病率的下降,并且 MIR 显著降低。同时,前列腺癌的生存率也得到了改善。

结论

发展对泌尿生殖系统癌症的结局有显著影响。HDI 值与癌症发病率、MIR 和生存率显著相关。近年来,HDI 值随着泌尿生殖系统癌症发病率的增加和结局的改善而上升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/abe859657299/12894_2022_953_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/eeb26f400cce/12894_2022_953_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/35b47cb9e8b4/12894_2022_953_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/2908f1ecdc75/12894_2022_953_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/492908f1d36c/12894_2022_953_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/abe859657299/12894_2022_953_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/eeb26f400cce/12894_2022_953_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/35b47cb9e8b4/12894_2022_953_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/2908f1ecdc75/12894_2022_953_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/492908f1d36c/12894_2022_953_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17a9/8744298/abe859657299/12894_2022_953_Fig5_HTML.jpg

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