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两起医院感染爆发和假爆发事件的报告,原因是被不动杆菌属污染。

Report of two events of nosocomial outbreak and pseudo-outbreak due to contamination with Achromobacter spp.

机构信息

Hospital Italiano de Buenos Aires, Sección Infectología, Servicio de Clínica Médica, Pres. Tte. Gral. Juan Domingo Perón 4190, Ciudad Autónoma de Buenos Aires, C1199, Argentina; Hospital Italiano de Buenos Aires, Comité de Control de Infecciones, Pres. Tte. Gral. Juan Domingo Perón 4190, Ciudad Autónoma de Buenos Aires, C1199, Argentina.

Hospital Italiano de Buenos Aires, Sección Infectología, Servicio de Clínica Médica, Pres. Tte. Gral. Juan Domingo Perón 4190, Ciudad Autónoma de Buenos Aires, C1199, Argentina.

出版信息

Rev Argent Microbiol. 2022 Jul-Sep;54(3):175-180. doi: 10.1016/j.ram.2021.10.004. Epub 2022 Jan 7.

DOI:10.1016/j.ram.2021.10.004
PMID:35012807
Abstract

Achromobacter spp. are increasingly recognized as emerging pathogens in immunocompromised patients or suffering cystic fibrosis, but unusual in immunocompetent hosts or individuals that underwent surgery. In this study we describe two simultaneous events attributable to two different Achromobacter spp. contaminated sources. One event was related to an episode of pseudo-bacteremia due to sodium citrate blood collection tubes contaminated with Achromobacter insuavis and the other to Achromobacter genogroup 20 infection and colonization caused by an intrinsically contaminated chlorhexidine soap solution. Both threatened the appropriate use of antimicrobials. Molecular approaches were critical to achieving the accurate species identification and to assess the clonal relationship, strengthening the need for dedicated, multidisciplinary and collaborative work of microbiologists, specialists in infectious diseases, epidemiologists and nurses in the control of infections to clarify these epidemiological situations.

摘要

不动杆菌属越来越被认为是免疫功能低下患者或患有囊性纤维化的新兴病原体,但在免疫功能正常的宿主或接受过手术的个体中并不常见。在本研究中,我们描述了两起由两种不同的不动杆菌属污染来源引起的同时发生的事件。一起事件与柠檬酸血液采集管被无色杆菌污染导致的假性菌血症有关,另一起事件与内在污染的洗必泰肥皂溶液引起的不动杆菌属基因群 20 感染和定植有关。这两起事件都威胁到了抗菌药物的合理使用。分子方法对于实现准确的物种鉴定和评估克隆关系至关重要,这加强了微生物学家、传染病专家、流行病学家和护士在感染控制方面进行专门的、多学科和协作工作的必要性,以澄清这些流行病学情况。

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