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罕见但灾难性的未诊断抗磷脂综合征表现。

Rare yet catastrophic presentation of undiagnosed antiphospholipid syndrome.

机构信息

General Medicine, Tamworth Rural Referral Hospital, Tamworth, New South Wales, Australia

General Medicine, Tamworth Rural Referral Hospital, Tamworth, New South Wales, Australia.

出版信息

BMJ Case Rep. 2022 Jan 10;15(1):e245838. doi: 10.1136/bcr-2021-245838.

Abstract

A previously well 31-year-old woman initially presented to the emergency department with pneumonia, however, was found to be hypertensive and have new-onset cardiomegaly. She was admitted for intravenous antibiotics and concurrently a series of investigations were conducted to investigate hypertension and cardiomegaly. During the course of admission, she developed acute kidney injury and was found to have acute chronic occlusion in the abdominal aorta. She was diagnosed with catastrophic antiphospholipid syndrome. This is a rare form of antiphospholipid syndrome with a high mortality rate. Thus, it is important that clinicians are aware of this syndrome to facilitate early diagnosis and initiation of treatment.

摘要

一位原本健康的 31 岁女性最初因肺炎到急诊就诊,但被发现患有高血压和新发的心脏扩大。她被收治入院接受静脉抗生素治疗,同时进行了一系列检查以明确高血压和心脏扩大的原因。在住院期间,她发生了急性肾损伤,并且被发现腹主动脉急性慢性闭塞。她被诊断为灾难性抗磷脂综合征。这是一种罕见的抗磷脂综合征形式,死亡率很高。因此,临床医生了解这种综合征以促进早期诊断和治疗非常重要。

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Diagnosis and management of catastrophic antiphospholipid syndrome.灾难性抗磷脂综合征的诊断与治疗。
Expert Rev Hematol. 2017 Apr;10(4):365-374. doi: 10.1080/17474086.2017.1300522. Epub 2017 Mar 13.

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