Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM, 87106, USA.
Department of Data Sciences, University of Mississippi Medical Center, Jackson, MS, USA.
J Clin Psychol Med Settings. 2022 Dec;29(4):739-749. doi: 10.1007/s10880-021-09841-w. Epub 2022 Jan 10.
The development of substance abuse in youth with asthma have seldom been examined with longitudinal research. The prospective and well-characterized CAMP cohort provides outcome data on youth with asthma over 13 years. This manuscript seeks to determine the contributions of asthma features and child behavioral/emotional functioning to subsequent tobacco, alcohol, and drug use in early adulthood. Childhood smoking exposures as well as parent report and youth report of substance use were prospectively assessed concurrently with assessments of asthma symptoms, study medication, and lung development. Logistic regression models evaluated predictors of adolescent and young adult tobacco, alcohol, and drug use. Use of tobacco products was reported by 33% of youth with mild/moderate asthma. Tobacco use was significantly associated with self-reported externalizing behaviors. Early life passive smoke exposure, especially in utero exposure, makes a significant contribution to tobacco use (OR1.58). Greater risk for tobacco use is conveyed by self-reported externalizing behaviors, which are consistently robust predictors of any future use of tobacco products, alcohol and drugs. These findings provide evidence for health care providers to use routine behavioral screening in youth with asthma.
青少年哮喘患者的物质滥用发展很少通过纵向研究来检验。前瞻性且特征明确的 CAMP 队列为哮喘青少年提供了超过 13 年的结局数据。本研究旨在确定哮喘特征和儿童行为/情绪功能对青少年后期烟草、酒精和药物使用的影响。儿童期吸烟暴露以及父母报告和青少年自我报告的物质使用与哮喘症状、研究药物和肺发育同时进行前瞻性评估。逻辑回归模型评估了青少年和年轻成人吸烟、饮酒和药物使用的预测因素。33%的轻度/中度哮喘青少年报告使用烟草制品。烟草使用与自我报告的外向行为显著相关。生命早期的被动吸烟暴露，尤其是宫内暴露，对吸烟有显著影响（OR1.58）。自我报告的外向行为预示着更大的烟草使用风险，它是未来使用任何烟草制品、酒精和药物的一致强预测因素。这些发现为医疗保健提供者在哮喘青少年中进行常规行为筛查提供了证据。
