Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, India.
Division of Non-Communicable Diseases, Indian Council of Medical Research (ICMR), New Delhi, India.
J Basic Microbiol. 2022 Sep;62(9):999-1029. doi: 10.1002/jobm.202100477. Epub 2022 Jan 11.
Microalgae and cyanobacteria (blue-green algae) are used as food by humans. They have gained a lot of attention in recent years because of their potential applications in biotechnology. Microalgae and cyanobacteria are good sources of many valuable compounds, including important biologically active compounds with antiviral, antibacterial, antifungal, and anticancer activities. Under optimal growth condition and stress factors, algal biomass produce varieties of potential bioactive compounds. In the current review, bioactive compounds production and their remarkable applications such as pharmaceutical and nutraceutical applications along with processes involved in identification and characterization of the novel bioactive compounds are discussed. Comprehensive knowledge about the exploration, extraction, screening, and trading of bioactive products from microalgae and cyanobacteria and their pharmaceutical and other applications will open up new avenues for drug discovery and bioprospecting.
微藻和蓝藻（蓝绿藻）被人类用作食物。近年来，由于它们在生物技术中的潜在应用，引起了人们的广泛关注。微藻和蓝藻是许多有价值化合物的良好来源，包括具有抗病毒、抗菌、抗真菌和抗癌活性的重要生物活性化合物。在最佳生长条件和胁迫因素下，藻类生物量会产生多种潜在的生物活性化合物。在本综述中，讨论了生物活性化合物的生产及其在制药和营养保健品等方面的显著应用，以及鉴定和表征新型生物活性化合物所涉及的过程。对微藻和蓝藻生物活性产物的开发、提取、筛选和贸易及其在制药等方面的应用的综合了解，将为药物发现和生物勘探开辟新途径。
