Chemistry Department, University of Hawaii at Manoa, Honolulu, Hawaii 96822, United States.
Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, United States.
J Org Chem. 2022 Jan 21;87(2):1559-1563. doi: 10.1021/acs.joc.1c02583. Epub 2022 Jan 11.
We have developed robust, operationally simple syntheses of fluorenes and of dibenzo[]chrysenes through oxidative cascade processes. These structures that are commonly encountered in optoelectronic materials, dyes, and pharmaceutical products are accessible from 1,4-dioxaspiro[4.5]decan-8-one. The reactions are conducted open to air with inexpensive, safe CuBr or CuCl.
我们开发了通过氧化级联过程制备芴和二苯并[]咔唑的稳健、操作简单的合成方法。这些在光电材料、染料和药物产品中常见的结构可以从 1,4-二氧杂螺[4.5]癸烷-8-酮得到。反应在敞开的空气中进行，使用廉价、安全的 CuBr 或 CuCl 作为催化剂。
