Department of general thoracic surgery, Yamanashi University, Yamanashi, Japan.
Thorac Cancer. 2022 Feb;13(4):653-655. doi: 10.1111/1759-7714.14316. Epub 2022 Jan 11.
The lung is the most common site of metastasis in patients with renal cell carcinoma (RCC). Metastatic RCCs, even those classified as stage I, can recur after >10 years. Therefore, it is critical to completely resect metastatic nodules. Here, we report the case of a 74-year-old man who underwent a nephrectomy for RCC and was diagnosed with lung metastasis 17 years later. The metastatic nodule was resected through complete thoracoscopic subsegmentectomy. He had previously undergone partial nephrectomy for clear cell renal carcinoma pT1bN0M0. During his annual follow-up, a computed tomography scan revealed a pulmonary nodule. The intraoperative frozen section revealed a metastatic clear cell RCC. Thus, additional lobectomy was not performed. The postoperative course was uneventful with no complications. This case demonstrates that even early stage metastatic clear cell renal carcinoma can recur after over 17 years. Thoracoscopic segmentectomy is less invasive and can preserve pulmonary function.
肺是肾细胞癌(RCC)患者最常见的转移部位。转移性 RCC 即使被归类为 I 期,也可能在 >10 年后复发。因此,完全切除转移结节至关重要。在这里,我们报告了一名 74 岁男性的病例,他因 RCC 接受了肾切除术,17 年后被诊断为肺转移。通过完全胸腔镜亚段切除术切除了转移结节。他之前因透明细胞肾细胞癌 pT1bN0M0 接受了部分肾切除术。在他的年度随访中,计算机断层扫描显示肺部有一个结节。术中冷冻切片显示为转移性透明细胞 RCC。因此,未进行额外的肺叶切除术。术后过程顺利,无并发症。该病例表明,即使是早期转移性透明细胞肾细胞癌也可能在 17 年以上后复发。胸腔镜节段切除术具有较小的侵袭性,并能保留肺功能。