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CLinical Assessment of WEB device in Ruptured aneurYSms (CLARYS): results of 1-month and 1-year assessment of rebleeding protection and clinical safety in a multicenter study.WEB 装置治疗破裂动脉瘤的临床评估(CLARYS):多中心研究中 1 个月和 1 年评估再出血保护和临床安全性的结果。
J Neurointerv Surg. 2022 Aug;14(8):807-814. doi: 10.1136/neurintsurg-2021-017416. Epub 2021 Sep 7.
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eCLIPs bifurcation remodeling system for treatment of wide neck bifurcation aneurysms with extremely low dome-to-neck and aspect ratios: a multicenter experience.eCLIPs 分叉重建系统治疗极低瘤颈比和宽高比分叉部动脉瘤的多中心经验。
J Neurointerv Surg. 2021 May;13(5):438-442. doi: 10.1136/neurintsurg-2020-016354. Epub 2020 Aug 11.
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Efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm-A systematic review and meta-analysis.PulseRider 治疗宽颈颅内动脉瘤的疗效和安全性:系统评价和荟萃分析。
Interv Neuroradiol. 2021 Feb;27(1):60-67. doi: 10.1177/1591019920940521. Epub 2020 Jul 7.
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Aneurysm treatment with WEB in the cumulative population of two prospective, multicenter series: 3-year follow-up.WEB 治疗动脉瘤的累积人群的前瞻性、多中心系列研究:3 年随访结果。
J Neurointerv Surg. 2021 Apr;13(4):363-368. doi: 10.1136/neurintsurg-2020-016151. Epub 2020 Jun 12.
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Use of the pCONus HPC as an adjunct to coil occlusion of acutely ruptured aneurysms: early clinical experience using single antiplatelet therapy.使用 pCONus HPC 作为急性破裂动脉瘤线圈闭塞的辅助手段:使用单一抗血小板治疗的早期临床经验。
J Neurointerv Surg. 2020 Sep;12(9):862-868. doi: 10.1136/neurintsurg-2019-015746. Epub 2020 Feb 26.
6
The Contour-Early Human Experience of a Novel Aneurysm Occlusion Device.新型颅内动脉瘤闭塞装置的 Contour 早期人体体验
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Endovascular treatment of wide-necked intracranial aneurysms using the novel Contour Neurovascular System: a single-center safety and feasibility study.采用新型 Contour Neurovascular System 血管内治疗宽颈颅内动脉瘤:单中心安全性和可行性研究。
J Neurointerv Surg. 2020 Oct;12(10):987-992. doi: 10.1136/neurintsurg-2019-015628. Epub 2020 Jan 22.
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Stent-assisted coiling of cerebral aneurysms: multi-center analysis of radiographic and clinical outcomes in 659 patients.支架辅助弹簧圈栓塞治疗颅内动脉瘤:659 例患者的影像学和临床结局的多中心分析。
J Neurointerv Surg. 2020 Mar;12(3):289-297. doi: 10.1136/neurintsurg-2019-015182. Epub 2019 Sep 17.
9
The safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide-necked bifurcation aneurysms: final 12-month results of the pivotal WEB Intrasaccular Therapy (WEB-IT) Study.Woven EndoBridge(WEB)系统治疗宽颈分叉动脉瘤的安全性和有效性:关键性 WEB 腔内治疗(WEB-IT)研究的最终 12 个月结果。
J Neurointerv Surg. 2019 Sep;11(9):924-930. doi: 10.1136/neurintsurg-2019-014815. Epub 2019 Apr 16.
10
Factors that determine aneurysm occlusion after embolization with the Woven EndoBridge (WEB).影响 WEB 栓塞后动脉瘤闭塞的因素。
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微导管内圈辅助栓塞治疗宽颈颅内动脉瘤的效果(CoCoJaMBO):初步原理和即刻血管造影结果。

Contour-Assisted coiling with jailed microcatheter May result in better occlusion (CoCoJaMBO) in wide-necked intracranial aneurysms: Proof of principle and immediate angiographic results.

机构信息

Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Campus Kiel, Christian-Albrechts University, Germany.

Institute of Neuroradiology, LMU-University Hospital, Ludwig-Maximilians-University, Munich, Germany.

出版信息

Interv Neuroradiol. 2023 Feb;29(1):79-87. doi: 10.1177/15910199211069782. Epub 2022 Jan 11.

DOI:10.1177/15910199211069782
PMID:35014885
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9893242/
Abstract

PURPOSE

Wide-necked bifurcation aneurysms, partially thrombosed, and recurrences of large and giant aneurysms are challenging to treat. We report our preliminary experience with a Contour-assisted coiling technique and discuss the periprocedural safety, feasibility, and effectiveness of the approach.

METHODS

We retrospectively reviewed consecutive patients who received endovascular treatment for intracranial aneurysms with an intra-aneurysmal flow disruptor (Contour) at two neurovascular centres between October 2018 and December 2020 and identified patients treated with a combination of Contour and platinum coils. Clinical and procedural data were recorded.

RESULTS

For this analysis, 8 patients (5 female) aged 60.1  ±  9.2 years on average were identified. Three of 8 aneurysms were associated with previous acute subarachnoid hemorrhage (SAH). The mean average dome height was 12.8  ±  7.6 mm, mean maximum dome width 10.3  ±  5.4 mm, and neck width 5.5  ±  2.5 mm. The mean dome-to-neck ratio was 1.9  ±  1.0. Immediate complete occlusion of the aneurysm was seen in 5 of 8 cases. In one SAH patient, a parent vessel was temporarily occluded but could be reopened rapidly. One device detached prematurely without any sequelae. No other procedural adverse events were recorded.

CONCLUSION

From this initial experience, Contour with adjunctive coiling is a safe and technically feasible method for endovascular treatment of large, wide-necked, partially thrombosed, recurrent, or ruptured bifurcation aneurysms. Further studies with larger numbers of patients and longer follow-up are needed to confirm our results.

摘要

目的

宽颈分叉部动脉瘤、部分血栓形成以及大型和巨大型动脉瘤的复发是具有挑战性的治疗对象。我们报告使用 Contour 辅助弹簧圈技术的初步经验,并讨论该方法的围手术期安全性、可行性和有效性。

方法

我们回顾性分析了 2018 年 10 月至 2020 年 12 月期间在两个神经血管中心接受颅内动脉瘤血管内治疗且使用了动脉瘤内血流阻断装置(Contour)的连续患者,并确定了使用 Contour 和铂金弹簧圈联合治疗的患者。记录临床和手术数据。

结果

本分析共纳入 8 例患者(5 例女性),平均年龄为 60.1±9.2 岁。8 例动脉瘤中有 3 例与既往急性蛛网膜下腔出血(SAH)有关。平均瘤顶高度为 12.8±7.6 mm,最大瘤顶宽度为 10.3±5.4 mm,颈宽为 5.5±2.5 mm。瘤颈比的平均值为 1.9±1.0。8 例患者中有 5 例即刻完全闭塞动脉瘤。在 1 例 SAH 患者中,暂时闭塞了载瘤动脉,但可以迅速重新开放。1 个装置过早脱落,没有任何后遗症。未记录到其他手术不良事件。

结论

从最初的经验来看,使用 Contour 辅助弹簧圈进行血管内治疗大型、宽颈、部分血栓形成、复发或破裂的分叉部动脉瘤是一种安全且技术可行的方法。需要进一步进行更大规模患者和更长随访时间的研究来证实我们的结果。