大剂量静脉注射7S免疫球蛋白治疗后免疫性中性粒细胞减少症的长期缓解
Long-term remission of immune neutropenia after treatment with high-dose intravenous 7S-immunoglobulin.
作者信息
Mann K, Fateh-Moghadam A, Pfeiffer A, Samtleben W, Meyer G, Bartl R, Wiesneth M
机构信息
Medizinische Klinik II, Klinikum Grosshadern, München.
出版信息
Klin Wochenschr. 1987 Oct 15;65(20):985-8. doi: 10.1007/BF01717834.
PMID:3501502
Abstract
In a 61-year-old woman recurrent bacterial infections were caused by immune neutropenia which was resistant to high-dose cortisone and plasmapheresis. However, high-dose intravenous 7S-immunoglobulin therapy (30 g for 6 days) induced a long-term remission for 35 months. This treatment modality is safe and should be used as a first-line agent.
摘要
一名61岁女性反复发生细菌感染，病因是免疫性中性粒细胞减少症，该病症对大剂量可的松和血浆置换疗法耐药。然而，大剂量静脉注射7S免疫球蛋白治疗（6天内给予30克）诱导了长达35个月的长期缓解。这种治疗方式是安全的，应作为一线治疗药物使用。
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