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免疫性中性粒细胞减少症中的静脉注射免疫球蛋白

Intravenous immunoglobulin in immune neutropenia.

作者信息

Ventura A, Florean P, Pascone R, Perini R, Pocecco M, Lepore L

出版信息

Helv Paediatr Acta. 1986 Mar;41(6):495-500.

PMID:3583771
Abstract

Three patients with immune neutropenia successfully treated with high dose intravenous IgG (IV IgG) are described. In the first case, the neutropenia had not responded to standard steroid therapy; in the second case, very high doses of steroids were required in order to obtain and maintain remission. In the last case, the steroids were contraindicated because of an underlying immunologic disorder. We suggest that these 3 forms of immune neutropenia might be a good indication for IV IgG treatment.

摘要

本文描述了3例接受大剂量静脉注射免疫球蛋白(IV IgG)成功治疗的免疫性中性粒细胞减少症患者。第一例患者,中性粒细胞减少症对标准类固醇疗法无反应;第二例患者,为了获得并维持缓解需要非常高剂量的类固醇。在最后一例患者中,由于潜在的免疫疾病,类固醇治疗是禁忌的。我们认为这3种形式的免疫性中性粒细胞减少症可能是IV IgG治疗的良好指征。

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