INRS-Centre Armand-Frappier Santé Biotechnologie, Université du Québec, Laval, QC H7V 1B7, Canada.
Dalton Trans. 2022 Feb 8;51(6):2214-2218. doi: 10.1039/d1dt02766b.
Diels-Alder cycloadditions involving furans and maleimides are extensively used in organic chemistry and materials synthesis. Given the promising advances of organoruthenium complexes in therapy, we explored the possibility of exploiting such Diels-Alder linkages as a mean to modulate their biological properties.
呋喃和马来酰亚胺的 Diels-Alder 环加成反应在有机化学和材料合成中得到了广泛的应用。鉴于有机钌配合物在治疗方面的有希望的进展,我们探索了利用这种 Diels-Alder 键作为调节其生物性质的手段的可能性。