Kaur Kirandeep, Gurnani Bharat
Gomabai Netralaya and Research Centre
Vernal keratoconjunctivitis (VKC) is a recurrent, bilateral allergic inflammation of the conjunctiva. The episodes are often periodic and have seasonal recurrences. Seasonal exacerbations characterize the condition in the initial stages with a peak incidence during spring and summer. Over time, the condition tends to become perennial. VKC is a subtype of allergic conjunctivitis. Vernal keratoconjunctivitis (VKC) is a type of allergic conjunctivitis. Additional types include perennial and seasonal rhinoconjunctivitis, atopic keratoconjunctivitis, and giant papillary conjunctivitis.VKC is classified based on the area of ocular involvement into palpebral, limbal, and mixed forms. This involves the upper tarsal conjunctiva. There is a close association between the inflamed conjunctiva and the corneal epithelium, often leading to significant corneal disease. This typically affects bulbar conjunctiva in the palpebral area and typically affects the Black and Asian populations. This has features of both the palpebral and limbal forms. Arlt was the first to describe peri-limbal swelling in 1846. Horner and Tranta explained the white elevations at the limbus, and these were named as Horner-Tranta dots. Gabrielides studied conjunctival secretions; he found that eosinophils are the main components of these secretions.
春季角结膜炎（VKC）是一种复发性双侧结膜过敏性炎症。发作通常呈周期性且有季节性复发。在初始阶段，季节性加重是该疾病的特征，在春季和夏季发病率达到高峰。随着时间推移，病情往往会变为常年性。VKC是过敏性结膜炎的一种亚型。春季角结膜炎（VKC）是过敏性结膜炎的一种类型。其他类型包括常年性和季节性鼻结膜炎、特应性角结膜炎和巨乳头性结膜炎。VKC根据眼部受累区域分为睑结膜型、角膜缘型和混合型。 这涉及上睑结膜。炎症结膜与角膜上皮之间存在密切关联，常导致严重的角膜疾病。 这通常影响睑裂区的球结膜，并且通常影响黑人和亚洲人群。 这具有睑结膜型和角膜缘型的特征。阿尔特于1846年首次描述了角膜缘周围肿胀。霍纳和特兰塔解释了角膜缘处的白色隆起，这些被命名为霍纳 - 特兰塔结节。加布里埃利德斯研究了结膜分泌物；他发现嗜酸性粒细胞是这些分泌物的主要成分。
