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拉萨地区春季角结膜炎的特征:一项单中心观察性研究。

Characteristics of Vernal Keratoconjunctivitis in Lhasa: A Single-Center, Observational Study.

机构信息

Department of Ophthalmology, Peking University First Hospital, Peking University, Beijing, China.

Department of Ophthalmology, Tibet Autonomous Region People's Hospital, Lhasa, Tibet Autonomous Region, China.

出版信息

Ocul Immunol Inflamm. 2024 Jul;32(5):648-651. doi: 10.1080/09273948.2023.2190804. Epub 2023 Mar 29.

DOI:10.1080/09273948.2023.2190804
PMID:36989072
Abstract

The incidence of vernal keratoconjunctivitis (VKC) varies across different ethnicities and regions. To investigate the clinical features of VKC in Tibet, a single-center case series of VKC was retrospectively reviewed from a general hospital in Lhasa over one year. General data and typical manifestations were recorded. Horner-Trantas dots, limbal neovascularization, pseudogerontoxon and upper palpebral conjunctival papilla were seen in most of these patients. Patients with signs such as limbal pannus ( = 2.18,  < 0.05), pseudogerontoxon ( = 2.61,  < 0.05), and Horner-Trantas dots ( = 2.33,  < 0.05) appeared to have longer disease courses, while patients with upper palpebral conjunctival lesions had earlier onset times ( = 2.12,  < 0.05). The clinical signs of VKC on the Tibetan Plateau are more obvious, and the ocular surface is commonly and severely involved.

摘要

春季角结膜炎(VKC)的发病率在不同种族和地区有所不同。为了研究西藏 VKC 的临床特征,我们对拉萨一家综合医院一年多来的 VKC 进行了单中心病例系列回顾。记录了一般资料和典型表现。大多数患者可见 Horner-Trantas 点、角膜缘新生血管、假性老年环和上睑结膜乳头。具有角膜缘血管翳( = 2.18, < 0.05)、假性老年环( = 2.61, < 0.05)和 Horner-Trantas 点( = 2.33, < 0.05)等体征的患者似乎病程较长,而上睑结膜病变的患者发病时间更早( = 2.12, < 0.05)。青藏高原 VKC 的临床体征更明显,眼表常受累严重。

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