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[伤寒热及细菌携带状态下免疫反应机制的特征]

[Characteristics of the mechanisms of the immune response in typhoid fever and the bacterial carrier state].

作者信息

Pogorel'skaia L V, Kirzon S S, Cheredeev A N, Il'inskiĭ Iu A, Snisar' N A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1987 Nov(11):68-72.

PMID:3501649
Abstract

During the acute period of typhoid fever, as well as in the early and, partially, late convalescence periods, a considerable increase in the level of T-lymphocytes and their helper activity and, in some cases, in the number of B- and D-cells and the populations of neutrophils with receptors for C3 and Fc IgG was observed. In chronic carriers immune shifts of a different character have been recorded: an increase in suppressor activity and a decrease in the number of the above-mentioned neutrophils. These data prompt the use of immunological criteria for the prediction of chronic carrier state in typhoid fever.

摘要

在伤寒热急性期以及早期和部分晚期恢复期,观察到T淋巴细胞水平及其辅助活性显著增加,在某些情况下,B细胞、D细胞数量以及具有C3和Fc IgG受体的中性粒细胞群体也有所增加。在慢性带菌者中记录到了不同性质的免疫变化:抑制活性增加,上述中性粒细胞数量减少。这些数据促使人们使用免疫学标准来预测伤寒热的慢性带菌状态。

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