J Am Pharm Assoc (2003). 2022 May-Jun;62(3):757-765. doi: 10.1016/j.japh.2021.12.012. Epub 2021 Dec 24.
Pharmacists serve a critical role in providing health care, especially in medically underserved areas. Despite the opioid crisis and legislation in most states allowing pharmacists to dispense naloxone without a prescription from another provider, pharmacists face multiple barriers to dispensing naloxone.
This study tested the effectiveness of CONSIDER New Mexico, an innovative educational initiative designed to increase naloxone dispensing by pharmacies.
A quasi-experimental study was conducted in New Mexico in 2019-2020. Community pharmacists and pharmacy technicians were recruited from a purposive sample of pharmacies. Data were collected through pre- and postintervention surveys with 65 pharmacists and 44 technicians from 49 pharmacies. Data analysis included hybrid fixed-effects regression models of variables associated with pre-post intervention change in intent to dispense naloxone and generalized least squares with maximum likelihood estimation for pre-post intervention change in naloxone dispensing.
Positive intervention effects were observed for measures of normative beliefs, self-efficacy, and intent to dispense naloxone (P < 0.05). Changes in normative beliefs and self-efficacy were associated with greater intent to offer naloxone to patients (P < 0.05). In addition, the median number of naloxone prescriptions dispensed per month increased 3.5 times after intervention. A statistically significant positive association was observed between the intervention and naloxone dispensing after adjusting for other factors (P < 0.001). Pharmacies providing more than 4 additional health services were more likely to increase naloxone dispensing postintervention than pharmacies offering not more than 2 services (P < 0.01). This difference averaged 19 naloxone prescriptions per month. Estimated change in dispensing postintervention was statistically significantly lower at independent, clinic-based, and other pharmacies where an average of 36 fewer naloxone prescriptions were dispensed per month compared with chain drug stores (P = 0.03).
The CONSIDER New Mexico intervention effectively increased self-efficacy, intent to dispense, and naloxone dispensing. Findings will inform future research examining widespread dissemination and implementation of the intervention and the sustainability of intervention effects.
药剂师在提供医疗保健方面发挥着至关重要的作用,尤其是在医疗服务不足的地区。尽管阿片类药物危机和大多数州的立法允许药剂师无需另一位提供者的处方即可分发纳洛酮,但药剂师在分发纳洛酮方面面临着多种障碍。
本研究测试了 CONSIDER 新墨西哥州的有效性,这是一项创新的教育计划,旨在增加药店分发纳洛酮的数量。
2019-2020 年在新墨西哥州进行了一项准实验研究。从有目的的药店样本中招募了社区药剂师和药剂技术员。数据通过 65 名药剂师和 44 名药剂技术员在 49 家药店进行的干预前后调查收集。数据分析包括与干预前后意图分发纳洛酮变化相关的变量的混合固定效应回归模型,以及用于干预前后纳洛酮分发变化的广义最小二乘法和最大似然估计。
观察到与规范信念、自我效能和分发纳洛酮的意图相关的积极干预效果(P<0.05)。规范信念和自我效能的变化与提供纳洛酮给患者的意愿增加相关(P<0.05)。此外,干预后每月分发的纳洛酮处方中位数增加了 3.5 倍。在调整其他因素后,观察到干预与纳洛酮的分发之间存在统计学上显著的正相关(P<0.001)。提供超过 4 种额外健康服务的药店比仅提供不超过 2 种服务的药店更有可能在干预后增加纳洛酮的分发(P<0.01)。这种差异平均每月为 19 个纳洛酮处方。在独立的、以诊所为基础的和其他药店,预计干预后的分发变化较低,每月平均分发的纳洛酮处方减少 36 个,与连锁药店相比(P=0.03)。
CONSIDER 新墨西哥州的干预措施有效地提高了自我效能、分发意愿和纳洛酮的分发。研究结果将为未来研究提供信息,以检验该干预措施的广泛传播和实施以及干预效果的可持续性。