1981 - 1983年瑞典的流感嗜血杆菌脑膜炎
Haemophilus influenzae meningitis in Sweden 1981-1983.
作者信息
Trollfors B, Claesson B A, Strangert K, Taranger J
机构信息
Department of Paediatrics, University of Göteborg, Ostra Hospital, Sweden.
出版信息
Arch Dis Child. 1987 Dec;62(12):1220-3. doi: 10.1136/adc.62.12.1220.
Four hundred and seventy cases of meningitis caused by Haemophilus influenza in children and 30 cases in adults were identified in Sweden between 1981 and 1983. The age specific incidence in the most susceptible age group (0-4 years) was 31/100,000/year (440 cases), which is higher than previously reported from Europe. A further 30 cases were seen in children aged 5-14. The risk of developing H influenzae meningitis before the age of 15 was 1 in 669. There were 11 deaths (2%) and five cases of serious neurological sequelae among the children. Only 18 children (4%) had predisposing diseases. All but one of the 294 strains of H influenzae from children that had been serotyped were type b. Infections in adults differed from infections in children. Five of the adults died (17%), 12 had important predisposing diseases, and at least six of the infections were caused by non-typable strains. It is concluded that research into the prevention of invasive H influenzae infections in children should have high priority.
1981年至1983年期间，瑞典确诊了470例儿童流感嗜血杆菌引起的脑膜炎病例以及30例成人病例。在最易感年龄组（0至4岁）中，年龄特异性发病率为每年31/10万（440例），高于欧洲此前报告的发病率。5至14岁儿童中又发现了30例。15岁前患流感嗜血杆菌脑膜炎的风险为1/669。儿童中有11例死亡（2%）和5例严重神经后遗症。只有18名儿童（4%）有易感疾病。对294株已进行血清分型的儿童流感嗜血杆菌菌株进行检测，除1株外，其余均为b型。成人感染与儿童感染不同。5名成人死亡（17%），12名成人有重要的易感疾病，至少6例感染由不可分型菌株引起。结论是，儿童侵袭性流感嗜血杆菌感染的预防研究应具有高度优先性。
Zotero 插件